MAGOH

Drosophila flies produce unfit progeny when they have mutations in their {{Nihongo|mago nashi|孫なし|mago nashi|{{lit|grandchildless}}|lead=yes}} gene. The progeny have defects in germplasm assembly and germline development.

MAGOH interacts with RBM8A{{cite journal |last=Zhao |first=X F |author2=Nowak N J |author3=Shows T B |author4=Aplan P D |date=January 2000 |title=MAGOH interacts with a novel RNA-binding protein |journal=Genomics |volume=63 |issue=1 |pages=145–8 |location = UNITED STATES| issn = 0888-7543| pmid = 10662555 |doi = 10.1006/geno.1999.6064 }}{{cite journal |last=Kataoka |first=N |author2=Diem M D |author3=Kim V N |author4=Yong J |author5=Dreyfuss G |date=November 2001 |title=Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex |journal=EMBO J. |volume=20 |issue=22 |pages=6424–33 |location = England| issn = 0261-4189| pmid = 11707413 |doi = 10.1093/emboj/20.22.6424 |pmc=125744 }} and NXF1.

In Drosophila melanogaster, Mago Nashi and Tsunagi/Y14 are core components of the exon junction complex. They complex with novel zinc finger protein Ranshi, which is involved in oocyte differentiation.{{cite journal | vauthors = Lewandowski JP, Sheehan KB, Bennett PE Jr, Boswell RE | date = Mar 2010 | title = Mago Nashi, Tsunagi/Y14, and Ranshi form a complex that influences oocyte differentiation in Drosophila melanogaster| journal = Dev. Biol. | volume = 339 | issue = 2| pages = 307–19 | doi = 10.1016/j.ydbio.2009.12.035 | pmid = 20045686 | pmc = 2852135 }}

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