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MALL

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

{{Other uses|Mall (disambiguation){{!}}Mall}}

MAL-like protein is a protein that in humans is encoded by the MALL gene.{{cite journal |vauthors=Hildebrandt F, Otto E, Rensing C, Nothwang HG, Vollmer M, Adolphs J, Hanusch H, Brandis M | title = A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1 | journal = Nat Genet | volume = 17 | issue = 2 | pages = 149–53 |date=Nov 1997 | pmid = 9326933 | doi = 10.1038/ng1097-149 | s2cid = 38035697 }}{{cite web | title = Entrez Gene: MALL mal, T-cell differentiation protein-like| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7851}}

This gene encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid-enriched membrane (GEM) and cholesterol-enriched membrane rafts. It interacts with caveolin-1.

References

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Further reading

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  • {{cite journal |vauthors=Kurdina MI, Denisov LE |title=[An evaluation of the efficacy of dispensary care as a method for the active detection of skin melanoma] |journal=Klinicheskaia Meditsina |volume=70 |issue= 11–12 |pages= 68–70 |year= 1993 |pmid= 1294831 }}
  • {{cite journal |vauthors=Lautner-Rieske A, Thiebe R, Zachau HG |title=Searching for non-V kappa transcripts from the human immunoglobulin kappa locus |journal=Gene |volume=159 |issue= 2 |pages= 199–202 |year= 1995 |pmid= 7622049 |doi=10.1016/0378-1119(95)00161-X }}
  • {{cite journal |vauthors=Magyar JP, Ebensperger C, Schaeren-Wiemers N, Suter U |title=Myelin and lymphocyte protein (MAL/MVP17/VIP17) and plasmolipin are members of an extended gene family |journal=Gene |volume=189 |issue= 2 |pages= 269–75 |year= 1997 |pmid= 9168137 |doi=10.1016/S0378-1119(96)00861-X }}
  • {{cite journal | author=Saunier S |title=A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis |journal=Hum. Mol. Genet. |volume=6 |issue= 13 |pages= 2317–23 |year= 1998 |pmid= 9361039 |doi=10.1093/hmg/6.13.2317 |name-list-style=vanc| author2=Calado J | author3=Heilig R | display-authors=3 | last4=Silbermann | first4=F | last5=Benessy | first5=F | last6=Morin | first6=G | last7=Konrad | first7=M | last8=Broyer | first8=M | last9=Gubler | first9=MC | doi-access=free }}
  • {{cite journal | author=de Marco MC |title=BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells |journal=J. Biol. Chem. |volume=276 |issue= 25 |pages= 23009–17 |year= 2001 |pmid= 11294831 |doi= 10.1074/jbc.M009739200 |name-list-style=vanc| author2=Kremer L | author3=Albar JP | display-authors=3 | last4=Martinez-Menarguez | first4=JA | last5=Ballesta | first5=J | last6=Garcia-Lopez | first6=MA | last7=Marazuela | first7=M | last8=Puertollano | first8=R | last9=Alonso | first9=MA | doi-access=free }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-style=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki | doi-access=free }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-style=vanc| author2=Venkatesan K | author3=Hao T | display-authors=3 | last4=Hirozane-Kishikawa | first4=Tomoko | last5=Dricot | first5=Amélie | last6=Li | first6=Ning | last7=Berriz | first7=Gabriel F. | last8=Gibbons | first8=Francis D. | last9=Dreze | first9=Matija |bibcode=2005Natur.437.1173R |s2cid=4427026 }}

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