MAPRE3
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Microtubule-associated protein RP/EB family member 3 is a protein that in humans is encoded by the MAPRE3 gene.{{cite journal |vauthors=Renner C, Pfitzenmeier JP, Gerlach K, Held G, Ohnesorge S, Sahin U, Bauer S, Pfreundschuh M | title = RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells | journal = J Immunol | volume = 159 | issue = 3 | pages = 1276–83 |date=Aug 1997 | doi = 10.4049/jimmunol.159.3.1276 | pmid = 9233623 | s2cid = 23797920 | doi-access = free }}{{cite web | title = Entrez Gene: MAPRE3 microtubule-associated protein, RP/EB family, member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22924}}
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.
References
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Further reading
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- {{cite journal |vauthors=Juwana JP, Henderikx P, Mischo A, etal |title=EB/RP gene family encodes tubulin binding proteins |journal=Int. J. Cancer |volume=81 |issue= 2 |pages= 275–84 |year= 1999 |pmid= 10188731 |doi=10.1002/(SICI)1097-0215(19990412)81:2<275::AID-IJC18>3.0.CO;2-Z |s2cid=33232892 |doi-access=free }}
- {{cite journal |vauthors=Nakagawa H, Koyama K, Murata Y, etal |title=EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue |journal=Oncogene |volume=19 |issue= 2 |pages= 210–6 |year= 2000 |pmid= 10644998 |doi= 10.1038/sj.onc.1203308 |doi-access= |s2cid=2284265 }}
- {{cite journal |vauthors=Su LK, Qi Y |title=Characterization of human MAPRE genes and their proteins |journal=Genomics |volume=71 |issue= 2 |pages= 142–9 |year= 2001 |pmid= 11161807 |doi= 10.1006/geno.2000.6428 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Bu W, Su LK |title=Characterization of functional domains of human EB1 family proteins |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 49721–31 |year= 2004 |pmid= 14514668 |doi= 10.1074/jbc.M306194200 |doi-access= free }}
- {{cite journal |vauthors=Douglas MW, Diefenbach RJ, Homa FL, etal |title=Herpes simplex virus type 1 capsid protein VP26 interacts with dynein light chains RP3 and Tctex1 and plays a role in retrograde cellular transport |journal=J. Biol. Chem. |volume=279 |issue= 27 |pages= 28522–30 |year= 2004 |pmid= 15117959 |doi= 10.1074/jbc.M311671200 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, etal |title=CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex |journal=J. Cell Biol. |volume=168 |issue= 1 |pages= 141–53 |year= 2005 |pmid= 15631994 |doi= 10.1083/jcb.200405094 | pmc=2171674 }}
- {{cite journal |vauthors=Yeh TY, Chuang JZ, Sung CH |title=Dynein light chain rp3 acts as a nuclear matrix-associated transcriptional modulator in a dynein-independent pathway |journal=J. Cell Sci. |volume=118 |issue= Pt 15 |pages= 3431–43 |year= 2005 |pmid= 16079286 |doi= 10.1242/jcs.02472 |doi-access= free }}
- {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
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