MARCH6
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
E3 ubiquitin-protein ligase MARCH6 is an enzyme that in humans is encoded by the MARCH6 gene.{{cite journal |vauthors=Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = J Virol | volume = 78 | issue = 3 | pages = 1109–20 |date=Jan 2004 | pmid = 14722266 | pmc = 321412 | doi =10.1128/JVI.78.3.1109-1120.2004 }}{{cite web | title = Entrez Gene: MARCH6 membrane-associated ring finger (C3HC4) 6| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10299| accessdate = }}
Gene name error in Excel
{{Main|Microsoft Excel#Conversion_problems}}
Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH6 gene in Microsoft Excel.{{cite journal | vauthors = Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, Barrett JC, Weinstein JN | display-authors = 6 | title = Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics | journal = BMC Bioinformatics | volume = 5 | issue = 1 | pages = 80 | date = June 2004 | pmid = 15214961 | pmc = 459209 | doi = 10.1186/1471-2105-5-80 | doi-access = free }} This is due to Excel's autocorrect feature treating the text "MARCH6" as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.{{cite journal | vauthors = Ziemann M, Eren Y, El-Osta A | title = Gene name errors are widespread in the scientific literature | journal = Genome Biology | volume = 17 | issue = 1 | pages = 177 | date = August 2016 | pmid = 27552985 | pmc = 4994289 | doi = 10.1186/s13059-016-1044-7 | doi-access = free }} The issue can be prevented by using an alias name (such as MARCHF6), prepending with an apostrophe ('), or preformatting the cell as text.
See also
{{Portal|Biology}}
References
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Further reading
{{refbegin | 2}}
- {{cite journal |vauthors=Kreft SG, Wang L, Hochstrasser M |title=Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). |journal=J. Biol. Chem. |volume=281 |issue= 8 |pages= 4646–53 |year= 2006 |pmid= 16373356 |doi= 10.1074/jbc.M512215200 |doi-access= free }}
- {{cite journal |vauthors=Hassink G, Kikkert M, van Voorden S, etal |title=TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum. |journal=Biochem. J. |volume=388 |issue= Pt 2 |pages= 647–55 |year= 2005 |pmid= 15673284 |doi= 10.1042/BJ20041241 | pmc=1138973 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Swanson R, Locher M, Hochstrasser M |title=A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation. |journal=Genes Dev. |volume=15 |issue= 20 |pages= 2660–74 |year= 2001 |pmid= 11641273 |doi= 10.1101/gad.933301 | pmc=312819 }}
- {{cite journal |vauthors=Nagase T, Ishikawa K, Miyajima N, etal |title=Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 1 |pages= 31–9 |year= 1998 |pmid= 9628581 |doi=10.1093/dnares/5.1.31 |doi-access=free }}
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External links
- {{UCSC genome browser|MARCH6}}
- {{UCSC gene details|MARCH6}}
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