MBNL2
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Muscleblind-like protein 2 is a protein that in humans is encoded by the MBNL2 gene.{{cite journal |vauthors=Fardaei M, Rogers MT, Thorpe HM, Larkin K, Hamshere MG, Harper PS, Brook JD | title = Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells | journal = Hum Mol Genet | volume = 11 | issue = 7 | pages = 805–14 |date=Apr 2002 | pmid = 11929853 | doi =10.1093/hmg/11.7.805 | doi-access = free }}{{cite web | title = Entrez Gene: MBNL2 muscleblind-like 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10150}}
This gene encodes a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein. Drosophila muscleblind is a gene required for photoreceptor differentiation. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
References
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Further reading
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- {{cite journal | author=Adereth Y |title=RNA-dependent integrin α3 protein localization regulated by the Muscleblind-like protein MLP1 |journal=Nat. Cell Biol. |volume=7 |issue= 12 |pages= 1240–7 |year= 2006 |pmid= 16273094 |doi= 10.1038/ncb1335 | pmc=2365307 |name-list-style=vanc| author2=Dammai V | author3=Kose N | display-authors=3 | last4=Li | first4=Runzhao | last5=Hsu | first5=Tien }}
- {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-style=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Ho TH |title=Muscleblind proteins regulate alternative splicing |journal=EMBO J. |volume=23 |issue= 15 |pages= 3103–12 |year= 2005 |pmid= 15257297 |doi= 10.1038/sj.emboj.7600300 | pmc=514918 |name-list-style=vanc| author2=Charlet-B N | author3=Poulos MG | display-authors=3 | last4=Singh | first4=Gopal | last5=Swanson | first5=Maurice S | last6=Cooper | first6=Thomas A }}
- {{cite journal | author=Dunham A |title=The DNA sequence and analysis of human chromosome 13 |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 | pmc=2665288 |name-list-style=vanc| author2=Matthews LH | author3=Burton J | display-authors=3 | last4=Ashurst | first4=J. L. | last5=Howe | first5=K. L. | last6=Ashcroft | first6=K. J. | last7=Beare | first7=D. M. | last8=Burford | first8=D. C. | last9=Hunt | first9=S. E. |bibcode=2004Natur.428..522D }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal | author=Christian SL |title=An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia |journal=Genomics |volume=79 |issue= 5 |pages= 635–56 |year= 2002 |pmid= 11991713 |doi= 10.1006/geno.2002.6765 |name-list-style=vanc| author2=McDonough J | author3=Liu Cy CY | display-authors=3 | last4=Shaikh | first4=Sanober | last5=Vlamakis | first5=Vivian | last6=Badner | first6=Judith A | last7=Chakravarti | first7=Aravinda | last8=Gershon | first8=Elliot S }}
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External links
- {{UCSC genome browser|MBNL2}}
- {{UCSC gene details|MBNL2}}
Category:Biology of bipolar disorder
{{gene-13-stub}}