MCOLN2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Mucolipin-2 also known as TRPML2 (transient receptor potential cation channel, mucolipin subfamily, member 2) is a protein that in humans is encoded by the MCOLN2 gene.{{cite journal |vauthors=Clapham DE, Julius D, Montell C, Schultz G | title = International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 427–50 |date=December 2005 | pmid = 16382100 | doi = 10.1124/pr.57.4.6 | s2cid = 17936350 }} It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.

TRPML2 is associated with the Arf6-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.{{cite journal |vauthors=Karacsonyi C, Miguel AS, Puertollano R | title = Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs | journal = Traffic | volume = 8 | issue = 10 | pages = 1404–14 |date=October 2007 | pmid = 17662026 | doi = 10.1111/j.1600-0854.2007.00619.x | s2cid = 25624298 | url =https://zenodo.org/record/1000701 | doi-access = free }}