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MGAT5B

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B is an enzyme that in humans is encoded by the MGAT5B gene.{{cite journal |vauthors=Inamori K, Endo T, Gu J, Matsuo I, Ito Y, Fujii S, Iwasaki H, Narimatsu H, Miyoshi E, Honke K, Taniguchi N | title = N-Acetylglucosaminyltransferase IX acts on the GlcNAc beta 1,2-Man alpha 1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan | journal = J Biol Chem | volume = 279 | issue = 4 | pages = 2337–2340 |date=Jan 2004 | pmid = 14617637 | doi = 10.1074/jbc.C300480200 | doi-access = free }}{{cite journal |vauthors=Kaneko M, Alvarez-Manilla G, Kamar M, Lee I, Lee JK, Troupe K, Zhang W, Osawa M, Pierce M | title = A novel beta(1,6)-N-acetylglucosaminyltransferase V (GnT-VB)(1) | journal = FEBS Lett | volume = 554 | issue = 3 | pages = 515–519 |date=Nov 2003 | pmid = 14623122 | doi =10.1016/S0014-5793(03)01234-1 | s2cid = 82207739 | doi-access = free }}{{cite web | title = Entrez Gene: MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=146664}}

References

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Further reading

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  • {{cite journal |vauthors=Land A, Braakman I |title=Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum |journal=Biochimie |volume=83 |issue= 8 |pages= 783–790 |year= 2001 |pmid= 11530211 |doi=10.1016/S0300-9084(01)01314-1 |hdl=1874/5091 |s2cid=13576808 |hdl-access=free }}
  • {{cite journal |vauthors=Abbott KL, Troupe K, Lee I, Pierce M |title=Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb |journal=Exp. Cell Res. |volume=312 |issue= 15 |pages= 2837–2850 |year= 2006 |pmid= 16857188 |doi= 10.1016/j.yexcr.2006.05.022 }}
  • {{cite journal | author=Lee I |title=N-acetylglucosaminyltranferase VB expression enhances beta1 integrin- dependent PC12 neurite outgrowth on laminin and collagen |journal=J. Neurochem. |volume=97 |issue= 4 |pages= 947–956 |year= 2006 |pmid= 16606368 |doi= 10.1111/j.1471-4159.2006.03785.x |name-list-style=vanc| author2=Guo HB | author3=Kamar M | display-authors=3 | last4=Abbott | first4=Karen | last5=Troupe | first5=Karolyn | last6=Lee | first6=Jin-Kyu | last7=Alvarez-Manilla | first7=Gerardo | last8=Pierce | first8=Michael |s2cid=22339355 | doi-access=free }}
  • {{cite journal | author=Inamori K |title=Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain |journal=Biochim. Biophys. Acta |volume=1760 |issue= 4 |pages= 678–684 |year= 2006 |pmid= 16413118 |doi= 10.1016/j.bbagen.2005.11.019 |name-list-style=vanc| author2=Mita S | author3=Gu J | display-authors=3 | last4=Mizunohorikawa | first4=Y | last5=Miyoshi | first5=E | last6=Dennis | first6=J | last7=Taniguchi | first7=N }}
  • {{cite journal |vauthors=Guo HB, Lee I, Kamar M, Pierce M |title=N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways |journal=J. Biol. Chem. |volume=278 |issue= 52 |pages= 52412–52424 |year= 2004 |pmid= 14561752 |doi= 10.1074/jbc.M308837200 |doi-access= free }}
  • {{cite journal | author=Inamori K |title=Molecular cloning and characterization of human GnT-IX, a novel beta1,6-N-acetylglucosaminyltransferase that is specifically expressed in the brain |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 43102–43109 |year= 2003 |pmid= 12941944 |doi= 10.1074/jbc.M308255200 |name-list-style=vanc| author2=Endo T | author3=Ide Y | display-authors=3 | last4=Fujii | first4=S | last5=Gu | first5=J | last6=Honke | first6=K | last7=Taniguchi | first7=N | doi-access=free }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD | bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |vauthors=Papandreou MJ, Fenouillet E |title=Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation |journal=FEBS Lett. |volume=406 |issue= 1–2 |pages= 191–195 |year= 1997 |pmid= 9109416 |doi=10.1016/S0014-5793(97)00273-1 |s2cid=17660 |doi-access=free }}
  • {{cite journal | author=Bolmstedt A |title=Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 3 |pages= 213–20 |year= 1996 |pmid= 8673525 |doi=10.1097/00042560-199607000-00001 |name-list-style=vanc| author2=Sjölander S | author3=Hansen JE | display-authors=3 | last4=Akerblom | first4=L | last5=Hemming | first5=A | last6=Hu | first6=SL | last7=Morein | first7=B | last8=Olofsson | first8=S | doi-access=free }}
  • {{cite journal | author=Fenouillet E |title=Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain |journal=J. Virol. |volume=67 |issue= 1 |pages= 150–60 |year= 1993 |pmid= 8093218 |doi= 10.1128/jvi.67.1.150-160.1993| pmc=237347 |name-list-style=vanc| author2=Jones I | author3=Powell B | display-authors=3 | last4=Schmitt | first4=D | last5=Kieny | first5=MP | last6=Gluckman | first6=JC }}
  • {{cite journal |vauthors=Montefiori DC, Robinson WE, Mitchell WM |title=Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 23 |pages= 9248–9252 |year= 1988 |pmid= 3264072 |doi=10.1073/pnas.85.23.9248 | pmc=282716 |bibcode=1988PNAS...85.9248M |doi-access=free }}
  • {{cite journal | author=Blough HA |title=Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins |journal=Biochem. Biophys. Res. Commun. |volume=141 |issue= 1 |pages= 33–38 |year= 1987 |pmid= 3099781 |doi=10.1016/S0006-291X(86)80330-8 |name-list-style=vanc| author2=Pauwels R | author3=De Clercq E | display-authors=3 | last4=Cogniaux | first4=J | last5=Sprechergoldberger | first5=S | last6=Thiry | first6=L }}
  • {{cite journal |vauthors=Robinson WE, Montefiori DC, Mitchell WM |title=Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis |journal=AIDS Res. Hum. Retroviruses |volume=3 |issue= 3 |pages= 265–282 |year= 1988 |pmid= 2829950 |doi=10.1089/aid.1987.3.265 }}
  • {{cite journal | author=Kozarsky K |title=Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein |journal=J. Acquir. Immune Defic. Syndr. |volume=2 |issue= 2 |pages= 163–9 |year= 1989 |pmid= 2649653 |name-list-style=vanc| author2=Penman M | author3=Basiripour L | display-authors=3 | last4=Haseltine | first4=W | last5=Sodroski | first5=J | last6=Krieger | first6=M }}
  • {{cite journal |vauthors=Pal R, Hoke GM, Sarngadharan MG |title=Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 9 |pages= 3384–3388 |year= 1989 |pmid= 2541446 |doi=10.1073/pnas.86.9.3384 | pmc=287137 |bibcode=1989PNAS...86.3384P |doi-access=free }}
  • {{cite journal | author=Kalyanaraman VS |title=Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1 |journal=AIDS Res. Hum. Retroviruses |volume=6 |issue= 3 |pages= 371–380 |year= 1990 |pmid= 2187500 |doi=10.1089/aid.1990.6.371 |name-list-style=vanc| author2=Rodriguez V | author3=Veronese F | display-authors=3 | last4=Rahman | first4=R. | last5=Lusso | first5=P. | last6=Devico | first6=A.L. | last7=Copeland | first7=T. | last8=Oroszlan | first8=S. | last9=Gallo | first9=R.C. |url=https://zenodo.org/record/1235229 }}
  • {{cite journal |vauthors=Dedera DA, Gu RL, Ratner L |title=Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function |journal=Virology |volume=187 |issue= 1 |pages= 377–382 |year= 1992 |pmid= 1736542 |doi=10.1016/0042-6822(92)90331-I }}

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