MIB1
{{Short description|Human enzyme}}
{{cs1 config|name-list-style=vanc}}{{for|the protein antibody|Ki-67 (protein)#MIB-1}}
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E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene.{{cite web | title = MIB1 MIB E3 ubiquitin protein ligase 1 [ Homo sapiens (human) ]| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57534| accessdate = 6 July 2023}} It is involved in regulating apoptosis.MIB1. OMIM.URL: [https://www.ncbi.nlm.nih.gov/omim/?term=608677 https://www.ncbi.nlm.nih.gov/omim/?term=608677]. Accessed on: April 24, 2009.
Confusion with proliferative marker
An antibody directed at the protein Ki-67, a product of the MKI67 gene, is called MIB-1.MIB-1. Veripath OncoDiagnostics. [http://www.oncodx.org/onco/mib_1.htm http://www.oncodx.org/onco/mib_1.htm] {{webarchive|url=https://web.archive.org/web/20060528205705/http://www.oncodx.org/onco/mib_1.htm |date=2006-05-28 }}. Accessed on: April 24, 2009.
References
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Further reading
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- {{cite journal |vauthors=Nagase T, Kikuno R, Ishikawa KI, etal |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 1 |pages= 65–73 |year= 2000 |pmid= 10718198 |doi=10.1093/dnares/7.1.65 |doi-access=free }}
- {{cite journal |vauthors=Wang Z, Tseng CP, Pong RC, etal |title=The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2. |journal=J. Biol. Chem. |volume=277 |issue= 15 |pages= 12622–31 |year= 2002 |pmid= 11812785 |doi= 10.1074/jbc.M110568200 |doi-access= free }}
- {{cite journal |vauthors=Jin Y, Blue EK, Dixon S, etal |title=A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 46980–6 |year= 2003 |pmid= 12351649 |doi= 10.1074/jbc.M208585200 |pmc=2824503|doi-access=free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Itoh M, Kim CH, Palardy G, etal |title=Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. |journal=Dev. Cell |volume=4 |issue= 1 |pages= 67–82 |year= 2003 |pmid= 12530964 |doi=10.1016/S1534-5807(02)00409-4 |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Henshall DC, Schindler CK, So NK, etal |title=Death-associated protein kinase expression in human temporal lobe epilepsy. |journal=Ann. Neurol. |volume=55 |issue= 4 |pages= 485–94 |year= 2004 |pmid= 15048887 |doi= 10.1002/ana.20001 |s2cid=35261517 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928}}
- {{cite journal |vauthors=Yoo KW, Kim EH, Jung SH, etal |title=Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish. |journal=FEBS Lett. |volume=580 |issue= 18 |pages= 4409–16 |year= 2006 |pmid= 16857196 |doi= 10.1016/j.febslet.2006.07.009 |s2cid=37762815 }}
- {{cite journal |vauthors=Song R, Koo BK, Yoon KJ, etal |title=Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. |journal=J. Biol. Chem. |volume=281 |issue= 47 |pages= 36391–400 |year= 2007 |pmid= 17003037 |doi= 10.1074/jbc.M606601200 |doi-access= free}}
- {{cite journal |vauthors=Zhang L, Nephew KP, Gallagher PJ |title=Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes. |journal=J. Biol. Chem. |volume=282 |issue= 16 |pages= 11795–804 |year= 2007 |pmid= 17324930 |doi= 10.1074/jbc.M610430200 |pmc=2823631|doi-access=free }}
- {{cite journal |vauthors=Yakut T, Gutenberg A, Bekar A, etal |title=Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas. |journal=Oncol. Rep. |volume=17 |issue= 5 |pages= 1037–43 |year= 2007 |pmid= 17390041 |doi= 10.3892/or.17.5.1037|doi-access=free }}
- {{cite journal |vauthors=van der Avoort IA, van der Laak JA, Paffen A, etal |title=MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva. |journal=Mod. Pathol. |volume=20 |issue= 7 |pages= 770–8 |year= 2007 |pmid= 17464313 |doi= 10.1038/modpathol.3800796 |doi-access= free |hdl= 2066/51438 |hdl-access= free }}
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