MYH8
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Myosin-8 is a protein that in humans is encoded by the MYH8 gene.{{cite journal |vauthors=Karsch-Mizrachi I, Feghali R, Shows TB, Leinwand LA | title = Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA | journal = Gene | volume = 89 | issue = 2 | pages = 289–94 |date=Aug 1990 | pmid = 2373371 | doi =10.1016/0378-1119(90)90020-R }}{{cite web | title = Entrez Gene: MYH8 myosin, heavy chain 8, skeletal muscle, perinatal| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4626}}
Mutations in MYH8 are associated with Trismus pseudocamptodactyly syndrome.
References
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Further reading
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- {{cite journal |vauthors=Bober E, Buchberger-Seidl A, Braun T, etal |title=Identification of three developmentally controlled isoforms of human myosin heavy chains. |journal=Eur. J. Biochem. |volume=189 |issue= 1 |pages= 55–65 |year= 1990 |pmid= 1691980 |doi=10.1111/j.1432-1033.1990.tb15459.x |doi-access=free }}
- {{cite journal |vauthors=Bober E, Lyons GE, Braun T, etal |title=The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development. |journal=J. Cell Biol. |volume=113 |issue= 6 |pages= 1255–65 |year= 1991 |pmid= 2045411 |doi=10.1083/jcb.113.6.1255 | pmc=2289041 }}
- {{cite journal |vauthors=Feghali R, Leinwand LA |title=Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. |journal=J. Cell Biol. |volume=108 |issue= 5 |pages= 1791–7 |year= 1989 |pmid= 2715179 |doi=10.1083/jcb.108.5.1791 | pmc=2115547 }}
- {{cite journal |vauthors=Jullian EH, Kelly AM, Pompidou AJ, etal |title=Characterization of a human perinatal myosin heavy-chain transcript. |journal=Eur. J. Biochem. |volume=230 |issue= 3 |pages= 1001–6 |year= 1995 |pmid= 7601129 |doi=10.1111/j.1432-1033.1995.tb20648.x }}
- {{cite journal |vauthors=Soussi-Yanicostas N, Whalen RG, Petit C |title=Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome. |journal=Hum. Mol. Genet. |volume=2 |issue= 5 |pages= 563–9 |year= 1993 |pmid= 8518795 |doi=10.1093/hmg/2.5.563 }}
- {{cite journal |vauthors=Veugelers M, Bressan M, McDermott DA, etal |title=Mutation of perinatal myosin heavy chain associated with a Carney complex variant. |journal=N. Engl. J. Med. |volume=351 |issue= 5 |pages= 460–9 |year= 2004 |pmid= 15282353 |doi= 10.1056/NEJMoa040584 |doi-access= free }}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Toydemir RM, Chen H, Proud VK, etal |title=Trismus-pseudocamptodactyly syndrome is caused by recurrent mutation of MYH8. |journal=Am. J. Med. Genet. A |volume=140 |issue= 22 |pages= 2387–93 |year= 2007 |pmid= 17041932 |doi= 10.1002/ajmg.a.31495 |s2cid=1775227 }}
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{{Cytoskeletal Proteins}}
{{gene-17-stub}}