MYL12B

{{Short description|Protein-coding gene in the species Homo sapiens}}

Myosin, light chain 12B, regulatory is a protein that in humans is encoded by the MYL12B gene.{{cite web | title = Myosin, light chain 12B, regulatory| url = https://www.ncbi.nlm.nih.gov/gene/103910| accessdate = 2011-12-05}} The gene is also known as MLC-B and MRLC2. The activity of nonmuscle myosin II is regulated by phosphorylation of a regulatory light chain, such as MYL12B. This phosphorylation results in higher ATPase activity and the assembly of myosin II filaments.{{Cite journal

| doi = 10.1247/csf.26.677

| last1 = Iwasaki | first1 = T.

| last2 = Murata-Hori | first2 = M.

| last3 = Ishitobi | first3 = S.

| last4 = Hosoya | first4 = H.

| title = Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells

| journal = Cell Structure and Function

| volume = 26

| issue = 6

| pages = 677–683

| year = 2001

| pmid = 11942626

| doi-access = free

}}