Magnesium glycinate
{{Short description|Chemical compound}}
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| Verifiedfields = changed
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| verifiedrevid =
| ImageFile = Magnesium diglycinate.svg
| IUPACName = Magnesium diglycinate
| SystematicName = Magnesium bis(aminoacetate)
| OtherNames =
|Section1={{Chembox Identifiers
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| ChemSpiderID_Ref =
| ChemSpiderID = 76358
| DrugBank = DB11189
| EC_number = 238-852-2
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 14783-68-7
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = IFN18A4Y6B
| PubChem = 84645
| StdInChI=1S/2C2H5NO2.Mg/c2*3-1-2(4)5;/h2*1,3H2,(H,4,5);/q;;+2/p-2
| StdInChIKey = AACACXATQSKRQG-UHFFFAOYSA-L
| SMILES = C(C(=O)[O-])N.C(C(=O)[O-])N.[Mg+2]
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|Section2={{Chembox Properties
| C=4 | H=8 | Mg=1 | N=2 | O=4
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|Section6={{Chembox Pharmacology
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Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycine (one magnesium atom and two glycine molecules), and is sold as a dietary supplement. It contains 14.1% elemental magnesium by mass.
Magnesium glycinate is also often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate{{Cite web |title=Magnesium Bisglycinate |url=https://88herbs.com/magnesium-bisglycinate/ |website=88Herbs|date= 20 November 2014}} form.
Uses
Magnesium glycinate has been studied with applicability to patients with a bowel resection{{cite journal | vauthors = Schuette SA, Lashner BA, Janghorbani M | title = Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection | journal = Journal of Parenteral and Enteral Nutrition | volume = 18 | issue = 5 | pages = 430–5 | year = 1994 | pmid = 7815675 | doi = 10.1177/0148607194018005430| quote = Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.}} or pregnancy-induced leg cramps.{{cite journal | vauthors = Supakatisant C, Phupong V | title = Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial | journal = Maternal & Child Nutrition | volume = 11 | issue = 2 | pages = 139–45 | year = 2015 | pmid = 22909270 | doi = 10.1111/j.1740-8709.2012.00440.x | quote = Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.| pmc = 6860204 }} Less scientific research exists on magnesium glycinate in therapeutic applications than other more common forms of magnesium salt such as magnesium chloride, oxide or citrate. Magnesium glycinate has been considered in the context of magnesium's potential influence on systems associated with the development of depression.{{Cite journal |last=Derom |first=Marie-Laure |last2=Sayón-Orea | first2=Carmen |last3=Martínez-Ortega |first3=José María |last4=Martínez-González |first4=Miguel A. |date=2013-09-01 |title=Magnesium and depression: a systematic review |url=https://www.tandfonline.com/doi/full/10.1179/1476830512Y.0000000044 |journal=Nutritional Neuroscience |volume=16 |issue=5 |pages=191–206 |doi=10.1179/1476830512Y.0000000044 |issn=1028-415X |pmid=23321048}}
File:Magnesium glycinate supplement Australia.jpg and extracts from Passiflora incarnata]]
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See also
References
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{{Mineral supplements}}
{{Magnesium compounds}}