Malonyl chloride

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| ImageFile = CH2(COCl)2.png

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| PIN = Propanedioyl dichloride{{cite book |author=International Union of Pure and Applied Chemistry |date=2014 |title=Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013 |publisher=The Royal Society of Chemistry |pages=797 |doi=10.1039/9781849733069 |isbn=978-0-85404-182-4}}

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| CASNo = 1663-67-8

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| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = PDF3ZL8FTK

| PubChem = 74269

| EC_number = 216-772-9

| ChemSpiderID = 66875

| InChI=1S/C3H2Cl2O2/c4-2(6)1-3(5)7/h1H2

| InChIKey = SXYFKXOFMCIXQW-UHFFFAOYSA-N

| SMILES = C(C(=O)Cl)C(=O)Cl

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| C=3 | O=2 | Cl = 2 | H=2

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| Appearance = colorless liquid

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| BoilingPtC = 58

| BoilingPt_notes = 28 mm Hg

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| GHSPictograms = {{GHS02}}{{GHS05}}

| GHSSignalWord= Danger

| HPhrases = {{H-phrases|226|314}}

| PPhrases = {{P-phrases|210|233|240|241|242|243|260|264|280|301+330+331|303+361+353|304+340|305+351+338|310|321|363|370+378|403+235|405|501}}

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Malonyl chloride is the organic compound with the formula CH2(COCl)2. It is the acyl chloride derivative of malonic acid. It is a colorless liquid although samples are often deeply colored owing to impurities. The compound degrades at room temperature after a few days. It used as a reagent in organic synthesis.{{Cite encyclopedia|encyclopedia=Encyclopedia of Reagents for Organic Synthesis|title=Malonyl Chloride|year=2001|doi=10.1002/047084289X.rm016|author=Thomas Ziegler|isbn=0471936235}}

Synthesis and reactions

Malonyl chloride can be synthesized from malonic acid in thionyl chloride.{{Cite journal|author= Chittaranjan Raha|title=Di-tert-Butyl Malonate|year=1953|volume=33|page=20|url=http://orgsyn.org/demo.aspx?prep=CV4P0261|journal=Organic Syntheses|doi=10.15227/orgsyn.034.0026|url-access=subscription}} As a bifunctional compound, it is used in the preparation of a number of cyclic compounds by diacylation. Heating in the presence of non-nucleophilic base gives the ketene derivative O=C=C(H)COCl.

References

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{{Navbox acyl chlorides}}

Category:Acyl chlorides

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