Mammaglobin-B
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Mammaglobin-B also known as secretoglobin family 2A member 1 is a protein that in humans is encoded by the SCGB2A1 gene.{{cite journal |vauthors=Becker RM, Darrow C, Zimonjic DB, Popescu NC, Watson MA, Fleming TP | title = Identification of mammaglobin B, a novel member of the uteroglobin gene family | journal = Genomics | volume = 54 | issue = 1 | pages = 70–8 |date=Jan 1999 | pmid = 9806831 | doi = 10.1006/geno.1998.5539 }}{{cite web | title = Entrez Gene: SCGB2A1 secretoglobin, family 2A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4246}}
SCGB2A1 and breast cancer
SCGB2A1 expression is highly specific of mammary tissue, and has been used for identification and detection of disseminated breast cancer cells.{{cite journal | first=M | last= Lacroix | title= Significance, detection and markers of disseminated breast cancer cells | journal=Endocrine-Related Cancer |publisher=Bioscientifica | year=2006 | volume=13 |pages=1033–1067| pmid=17158753| doi=10.1677/ERC-06-0001 | issue=4 | author-link=Marc Lacroix (biochemist)| doi-access=free }}
References
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Further reading
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- {{cite journal |vauthors=Molloy MP, Bolis S, Herbert BR, etal |title=Establishment of the human reflex tear two-dimensional polyacrylamide gel electrophoresis reference map: new proteins of potential diagnostic value. |journal=Electrophoresis |volume=18 |issue= 15 |pages= 2811–5 |year= 1998 |pmid= 9504814 |doi= 10.1002/elps.1150181516 |s2cid=39202047 }}
- {{cite journal |vauthors=Lehrer RI, Xu G, Abduragimov A, etal |title=Lipophilin, a novel heterodimeric protein of human tears. |journal=FEBS Lett. |volume=432 |issue= 3 |pages= 163–7 |year= 1998 |pmid= 9720917 |doi=10.1016/S0014-5793(98)00852-7 |s2cid=205880914 |doi-access=free |bibcode=1998FEBSL.432..163L }}
- {{cite journal |vauthors=Zhao C, Nguyen T, Yusifov T, etal |title=Lipophilins: human peptides homologous to rat prostatein. |journal=Biochem. Biophys. Res. Commun. |volume=256 |issue= 1 |pages= 147–55 |year= 1999 |pmid= 10066439 |doi= 10.1006/bbrc.1999.0274 }}
- {{cite journal |vauthors=Evans V, Vockler C, Friedlander M, etal |title=Lacryglobin in human tears, a potential marker for cancer. |journal=Clin. Experiment. Ophthalmol. |volume=29 |issue= 3 |pages= 161–3 |year= 2001 |pmid= 11446459 |doi=10.1046/j.1442-9071.2001.00408.x |s2cid=41723656 }}
- {{cite journal |vauthors=Carter D, Douglass JF, Cornellison CD, etal |title=Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer. |journal=Biochemistry |volume=41 |issue= 21 |pages= 6714–22 |year= 2002 |pmid= 12022875 |doi=10.1021/bi0159884 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Izmailova E, Bertley FM, Huang Q, etal |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 |s2cid=26145639 }}
- {{cite journal |vauthors=Sjödin A, Guo D, Sørhaug S, etal |title=Dysregulated secretoglobin expression in human lung cancers. |journal=Lung Cancer |volume=41 |issue= 1 |pages= 49–56 |year= 2003 |pmid= 12826312 |doi=10.1016/S0169-5002(03)00126-0 }}
- {{cite journal |vauthors=Ouellette RJ, Richard D, Maïcas E |title=RT-PCR for mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes. |journal=Am. J. Clin. Pathol. |volume=121 |issue= 5 |pages= 637–43 |year= 2004 |pmid= 15151203 |doi= 10.1309/MMAC-TXT5-5L8Q-TKC1 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Xiao F, Mirwald A, Papaioannou M, etal |title=Secretoglobin 2A1 is under selective androgen control mediated by a peculiar binding site for Sp family transcription factors. |journal=Mol. Endocrinol. |volume=19 |issue= 12 |pages= 2964–78 |year= 2006 |pmid= 16020486 |doi= 10.1210/me.2004-0408 |doi-access= free }}
- {{cite journal |vauthors=Bernstein JL, Godbold JH, Raptis G, etal |title=Identification of mammaglobin as a novel serum marker for breast cancer. |journal=Clin. Cancer Res. |volume=11 |issue= 18 |pages= 6528–35 |year= 2005 |pmid= 16166429 |doi= 10.1158/1078-0432.CCR-05-0415 |doi-access= free }}
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