Manchester score

Manchester score is an indicator of prognosis in small cell lung cancer.{{cite journal | last =Cerny | first =T |author2=Blair V |author3=Anderson H | title =Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients | journal =International Journal of Cancer | volume =39 | issue =2 | pages =146–149 | date =1987 | doi = 10.1002/ijc.2910390204| pmid =3026969 | s2cid =24194711 |display-authors=etal}}{{cite journal | last =Kawahara | first =Masaaki |author2=Masahiro Fukuoka |author3=Nagahiro Saijo | title =Prognostic factors and prognostic staging system for small cell lung cancer | journal =Japanese Journal of Clinical Oncology | volume =27 | issue =3 | pages =158–165 | publisher =Oxford University Press | date =1996 | doi = 10.1093/jjco/27.3.158| issn =0368-2811 | pmid =9255270 |display-authors=etal| doi-access =free }} It is calculated from a number of physical and biochemical markers.

A patient with small cell lung cancer scores one point for each of the following: {{cn|date=November 2020}}-

• Serum lactate dehydrogenase exceeds the upper limit of the reference range.
• Serum sodium concentration less than 132 mmol/L.
• Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
• Serum bicarbonate less than 24.
• Karnofsky performance status less than 60.
• Extensive stage disease.