Margaret Faul
{{short description|Irish American chemist}}
{{Use dmy dates|date=April 2022}}
{{Infobox scientist
| name = Margaret M. Faul
| alma_mater = University College Dublin
Harvard University
| thesis_year = 1992
| doctoral_advisor = David A. Evans
| known_for = Green chemistry, process science
}}
Margaret M. Faul is an Irish American chemist and executive who has won multiple awards for innovations in process chemistry.
Background
Faul received her undergraduate degrees from University College, Dublin before embarking on doctoral studies with Professor David A. Evans at Harvard. Her studies focused mostly on metal-catalyzed nitrene transfer reactions{{Cite journal|last=Evans|first=David A.|last2=Bilodeau|first2=Mark T.|last3=Faul|first3=Margaret M.|date=April 1994|title=Development of the Copper-Catalyzed Olefin Aziridination Reaction|journal=Journal of the American Chemical Society|language=EN|volume=116|issue=7|pages=2742–2753|doi=10.1021/ja00086a007|issn=0002-7863}} to produce aziridines, strained nitrogen precursors valued as pharmaceutical intermediates. Faul introduced multiple new wrinkles into this chemistry, including using chiral copper(I) catalysts{{Cite journal|last=Evans|first=David A.|last2=Faul|first2=Margaret M.|last3=Bilodeau|first3=Mark T.|last4=Anderson|first4=Benjamin A.|last5=Barnes|first5=David M.|date=June 1993|title=Bis(oxazoline)-copper complexes as chiral catalysts for the enantioselective aziridination of olefins|journal=Journal of the American Chemical Society|language=EN|volume=115|issue=12|pages=5328–5329|doi=10.1021/ja00065a068|issn=0002-7863}} to produce enantiomerically-enriched aziridines, and using a variety of different nitrene sources for the transfer.
Research
Faul joined the process chemistry group at Eli Lilly in 1993, and joined Amgen's process group in 2003, rising eventually to its Executive Director. According to a biosketch at Organic Syntheses, Faul has expertise in Good Manufacturing Process scale-up of both chemical and biological therapeutics, and coordinates groups of external partners through licensing, regulatory, and program development issues.{{Cite journal|last=Faul|first=Margaret|date=2017|title=Faul biosketch|url=http://www.orgsyn.org/content/pdfs/obits/margaretfaul.pdf|journal=Organic Syntheses|access-date=2018-11-19|archive-url=https://web.archive.org/web/20170721165631/http://www.orgsyn.org/content/pdfs/obits/margaretfaul.pdf|archive-date=2017-07-21|url-status=dead}} She attributes much of Amgen's success in this area to early adoption of new technologies, such as supercritical carbon dioxide purification and ultra-high performance liquid chromatography (uPLC).{{Cite journal|last=Patel|first=Prachi|date=2017-02-10|title=A Conversation with Margaret Faul|journal=ACS Central Science|language=EN|volume=3|issue=2|pages=141–142|doi=10.1021/acscentsci.7b00050|issn=2374-7943|pmc=5324089|pmid=28280781}}
Volunteer work
Faul is an Editorial Board member at Thieme journal Science of Synthesis.{{Cite news|url=https://www.thieme.de/en/thieme-chemistry/sos-editorial-board-55953.htm|title=Science of Synthesis Editorial Board - Thieme Chemistry - Georg Thieme Verlag|work=Thieme|access-date=2018-11-19|language=en-GB}} She has served as the chair of the Enabling Technologies Consortium.{{Cite news|url=https://www.thieme.de/en/thieme-chemistry/portrait-of-dr-margaret-faul-135857.htm|title=Portrait of Dr. Margaret Faul - Thieme Chemistry - Georg Thieme Verlag KG|work=Thieme|access-date=2018-11-19|language=en-GB}}{{Cite web|url=http://www.etconsortium.org/working-groups/|title=Working Groups|website=ETC|language=en-US|access-date=2018-11-19|archive-url=https://web.archive.org/web/20181119173539/http://www.etconsortium.org/working-groups/|archive-date=2018-11-19|url-status=dead}}
Awards and honors
- 2019 - Fellow of the American Chemical Society (ACS){{Cite web|url=https://www.acs.org/content/acs/en/funding-and-awards/fellows/list-of-2019-acs-fellows.html|title=2019 ACS Fellows|website=American Chemical Society|language=en|access-date=2019-08-12}}
- 2019 - Inaugural Margaret M. Faul Women in Chemistry Award, Thieme Publishers{{Cite news|url=https://www.thieme.de/en/thieme-chemistry/margaret-faul-women-in-chemistry-award-134016.htm|title=Women in Chemistry Award - Thieme Chemistry - Georg Thieme Verlag KG|work=Thieme|access-date=2018-11-19|language=en-GB}}
- 2018 - Earl B. Barnes award for Chemical Research Management, ACS{{Cite web|url=https://cen.acs.org/articles/96/i2/Earle-B-Barnes-Award-Leadership.html|title=Earle B. Barnes Award for Leadership in Chemical Research Management: Margaret M. Faul {{!}} January 8, 2018 Issue - Vol. 96 Issue 2 {{!}} Chemical & Engineering News|website=cen.acs.org|access-date=2018-11-19}}
- 2017 - Accepted the Presidential Green Chemistry Challenge award on behalf of Amgen Process{{Cite web|url=https://www.amgen.com/responsibility/environmental-sustainability/case-studies/green-chemistry-smart-science/|title=Amgen Wins the 2017 Green Chemistry Challenge Award|website=www.amgen.com|language=en|access-date=2018-11-19}}
- 1986 - Hugh Ryan Memorial Medal, UCD
References
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Category:American women chemists
Category:Year of birth missing (living people)
Category:Alumni of University College Dublin
Category:Harvard Graduate School of Arts and Sciences alumni
Category:21st-century American women
Category:20th-century Irish chemists
Category:21st-century Irish chemists
Category:20th-century Irish women scientists