Marie-Paule Kieny
{{short description|French virologist and science writer}}
{{Infobox scientist
| name = Marie-Paule Kieny
| image = File:M-Powering Development Initiative, First Advisory Board Meeting, ITU, Geneva, Switzerland. (10288754356).jpg
| nationality = French
| alma_mater = University of Montpellier; University of Strasbourg
}}
Marie-Paule Kieny is a French virologist, vaccinologist, public health expert and science writer. She is currently director of research at INSERM and chief of the board at DNDi.
Education
Kieny completed her PhD in microbiology in 1980 at the University of Montpellier, and received her Habilitation à Diriger des Recherches in 1995 from the University of Strasbourg.{{Cite web|url=https://www.elsevier.com/events/conferences/antivirals-congress/programme/speakers/biography-marie-paule-kieny|title=Biography Marie-Paule Kieny - Antivirals Congress - Elsevier|website=www.elsevier.com|access-date=2019-02-03}}
Kieny was presented with an honorary doctorate from the Autonomous University of Barcelona in 2019 for her commitment to public health and worldwide universal health care.{{Cite web|url=http://cerdanyola.info/societat/marie-paule-kieny-rep-el-doctorat-honoris-causa-de-la-uab-pel-seu-treball-en-pro-de-lacces-universal-a-la-salut/|title=Marie-Paule Kieny rep el doctorat honoris causa de la UAB pel seu treball per l'accés universal a la salut|language=es|access-date=2019-02-03}}{{Cite web|url=http://www.uab.cat/web/newsroom/news-detail/kieny-awarded-an-honorary-doctorate-for-her-undeniable-commitment-to-the-underprivileged-1345668003610.html?noticiaid=1345780524077|title=Kieny awarded an honorary doctorate for her "undeniable commitment" to the underprivileged|website=UAB Barcelona|language=en|access-date=2019-02-03}}{{Cite web|url=https://www.lavanguardia.com/vida/20190114/454130170477/la-uab-investira-doctora-honoris-causa-a-la-microbiologa-marie-paule-kieny.html|title=La UAB investirá doctora 'honoris causa' Marie-Paule Kieny por universalizar el acceso a la sanidad|date=2019-01-14|website=La Vanguardia|access-date=2019-02-03}}{{Cite web|url=https://www.europapress.es/catalunya/noticia-uab-investira-doctora-honoris-causa-marie-paule-kieny-universalizar-acceso-sanidad-20190114145951.html|title=La UAB investirá doctora 'honoris causa' Marie-Paule Kieny por universalizar el acceso a la sanidad|website=Europa Press|date=2019-01-14 |access-date=2019-02-03}}
Career
After completing her PhD, Kieny took up a position at Transgene SA, Strasbourg, as assistant scientific director under scientific director Jean-Pierre Lecocq until 1988.
Kieny became director of research at Inserm for the first time between 1999 and 2000. Kieny was a member of the European Vaccine Initiative until 2010.{{Cite web|url=http://www.euvaccine.eu/people/marie-paule-kieny|title=Marie-Paule Kieny {{!}} European Vaccine Initiative|website=www.euvaccine.eu|access-date=2019-02-03|archive-date=2017-07-12|archive-url=https://web.archive.org/web/20170712013700/http://www.euvaccine.eu/people/marie-paule-kieny}}
Kieny was vaccine research director of WHO from 2002 to 2010, most notably during the 2009 swine flu pandemic.{{Cite journal|last=Butler|first=Declan|date=2009-05-13|title=Marie-Paule Kieny|journal=Nature|doi=10.1038/news.2009.478|issn=0028-0836}}{{Cite web|url=https://www.prnewswire.com/news-releases/dr-marie-paule-kieny-appointed-to-the-human-vaccines-project-board-of-directors-300525753.html|title=Dr. Marie-Paule Kieny Appointed To The Human Vaccines Project Board Of Directors|publisher=Human Vaccines Project|website=www.prnewswire.com|language=en|access-date=2019-01-27}} She was promoted to assistant director-general, playing a major leadership role during the Ebola virus epidemic in West Africa and the 2015–16 Zika virus epidemic.{{Cite web|url=https://www.irishtimes.com/news/world/africa/who-expects-around-200-000-ebola-vaccine-doses-by-mid-2015-1.1976175|title=WHO expects around 200,000 Ebola vaccine doses by mid-2015|last=Nebehay|first=Stephanie|last2=Kell|first2=Kate|website=The Irish Times|language=en|access-date=2019-01-27}}{{Cite web|url=https://www.lifesciencesipreview.com/article/lsipr-50-2018-marie-paule-kieny-at-the-head-of-an-experiment-in-innovation|title=LSIPR 50 2018: At the head of an experiment in innovation|publisher=Newton Media|website=Life Sciences IP Review|language=en|access-date=2019-02-03}}{{Cite web|url=https://www.pharmaceutical-journal.com/news-and-analysis/news/who-lists-bacteria-that-need-to-be-targeted-for-antibiotic-development/20202399.article|title=WHO lists bacteria that need to be targeted for antibiotic development|last=Andalo|first=Debbie|website=Pharmaceutical Journal|language=en|access-date=2019-02-03}}{{Cite web|url=https://www.who.int/mediacentre/commentaries/zika-research-development/en/|archive-url=https://web.archive.org/web/20160217092147/http://www.who.int/mediacentre/commentaries/zika-research-development/en/|archive-date=February 17, 2016|title=WHO research and development on Zika|website=WHO|access-date=2019-03-03}} Kieny even audaciously signed up herself as a test subject for the safety of new Ebola vaccines being developed, amidst concerns over the logistics and ethics of testing early-stage therapeutics and preventatives for ebola in the context of an ongoing epidemic.{{Cite web|url=https://www.science.org/content/article/using-experimental-drugs-and-vaccines-against-ebola-ethical-who-panel-says|title=Using experimental drugs and vaccines against Ebola is ethical, WHO panel says|last=Kupferschmidt|first=Kai|date=2014-08-12|website=Science {{!}} AAAS|language=en|access-date=2019-03-03}}{{Cite web|url=https://www.biznews.com/health/health-briefs/2014/10/26/money-mouth-vaccines-boss-signs-first-ebola-trial-guinea-pig|title=WHO vaccines boss Marie-Paule Kieny signs up as first Ebola trial guinea pig|last=Sboros|first=Marika|date=2014-10-25|website=BizNews.com|language=en-GB|access-date=2019-02-03}} Given the slow development of new therapies in response to the outbreak, Kieny and colleagues began making a framework to speed up development and encourage researchers to share data openly without worrying about being scooped.{{Cite journal|last=Check Hayden|first=Erika|date=2015-05-28|title=Ebola teaches tough lessons about rapid research|url=http://www.nature.com/news/ebola-teaches-tough-lessons-about-rapid-research-1.17623|journal=Nature News|language=en|volume=521|issue=7553|pages=405–406|doi=10.1038/521405a|pmid=26017422|doi-access=free}} She commented on the successful development of efficacious vaccines for deployment in a future outbreak.{{Cite web|url=https://www.who.int/news-room/detail/23-12-2016-final-trial-results-confirm-ebola-vaccine-provides-high-protection-against-disease|title=Final trial results confirm Ebola vaccine provides high protection against disease|website=www.who.int|language=en|access-date=2019-03-03}} In aftermath of the 2014 Democratic Republic of the Congo Ebola virus outbreak Kieny stated that the vaccine may not be required since the outbreak was not as serious as previously feared.{{Cite web|url=https://www.statnews.com/2017/05/25/ebola-congo-update/|title=Ebola outbreak may be smaller than feared, WHO indicates|date=2017-05-25|website=STAT|language=en-US|access-date=2019-03-03}} Kieny was involved also in addressing the ongoing antimicrobial resistance crisis with WHO, overseeing the first WHO Model List of Essential Medicines to include guidance on proper use of antibiotics within the framework of universal health care.{{Cite web|url=https://www.healio.com/infectious-disease/antimicrobials/news/online/%7ba11fad55-9f04-4ec5-aad4-f708f27d26b2%7d/access-watch-reserve-who-committee-advises-when-to-use-common-antibiotics|title=Access, watch, reserve: WHO committee advises when to use common antibiotics|date=June 7, 2017|website=www.healio.com|language=en|access-date=2019-02-03}} She helped prepare a list of Antibiotic resistant bacteria which should be prioritised for research beyond just Extensively drug-resistant tuberculosis, such as Acinetobacter baumannii and Pseudomonas aeruginosa strains resistant to Carbapenem.{{Cite web|url=https://www.vox.com/2017/2/27/14750882/deadliest-superbugs-world-health-organization|title=The 12 most dangerous superbugs, ranked by the WHO|last=Belluz|first=Julia|author-link=Julia Belluz|date=2017-02-27|website=Vox|access-date=2019-03-03}}{{Cite web|url=https://www.statnews.com/2017/03/13/tuberculosis-who-bacteria-antibiotics/|title=WHO's priority list of antibiotic-resistant bacteria looks beyond tuberculosis|last=Kieny|first=Marie-Paule|date=2017-03-13|website=STAT|language=en-US|access-date=2019-03-03}}{{Cite news|url=https://www.nytimes.com/2017/02/27/health/who-bacteria-pathogens-antibiotic-resistant-superbugs.html|title=Deadly, Drug-Resistant 'Superbugs' Pose Huge Threat, W.H.O. Says|last=McNeil, Jr.|first=Donald G. |date=2017-02-27|work=The New York Times|access-date=2019-03-03|language=en-US|issn=0362-4331}}
Kieny was one of seven vaccine experts interviewed in 2012 by Wired about what the next decade held for vaccine innovation.{{Cite news|url=https://www.wired.co.uk/article/the-big-question-vaccines|title=The big question: What vaccines will we invent in the next decade?|last=Venkataramanan|first=Madhumita|date=2012-04-05|work=Wired UK|access-date=2019-01-27|issn=1357-0978}}
In 2017 she joined the board of directors for the Human Vaccines Project, was made interim director of the Medicines Patent Pool (MPP), and joined the Drugs for Neglected Diseases Initiative (DNDi) as chief of the board.{{Cite web|url=http://www.ip-watch.org/2018/02/08/leadership-change-interview-medicines-patent-pool-board-chair-marie-paule-kieny/|title=Leadership And Change: An Interview With Medicines Patent Pool Board Chair Marie-Paule Kieny|date=2018-02-08|website=Intellectual Property Watch|language=en-US|access-date=2019-01-27}}{{Cite web|url=https://www.dndi.org/about-dndi/our-people/board-directors/marie-paule-kieny/|title=Marie-Paule Kieny – DNDi|date=2017-08-15|website=DNDi – Best science for the most neglected|language=en-GB|access-date=2019-02-03}}{{Cite web|url=https://medicinespatentpool.org/mpp-media-post/the-medicines-patent-pool-governance-board-appoints-marie-paule-kieny-as-new-chair/|title=MPP-The Medicines Patent Pool Governance Board Appoints Marie-Paule Kieny as new Chair|language=en-GB|access-date=2019-02-03}} As head of MPP, Kieny oversaw the licensing of the Hepatitis C drug Mavyret for generic production.{{Cite web|url=https://www.healio.com/hepatology/hepatitis-c/news/online/%7bed6cde4f-e83a-45c0-b767-0c89cd1aec8f%7d/medicines-patent-pool-signs-license-for-generic-production-of-mavyret|title=Medicines Patent Pool signs license for generic production of Mavyret|date=December 3, 2018|website=www.healio.com|language=en|access-date=2019-03-03}}{{Cite web|url=https://www.thepharmaletter.com/article/abbvie-s-mavyret-shows-high-cure-rates|title=AbbVie's Mavyret shows high cure rates|website=www.thepharmaletter.com|access-date=2019-03-03}}
Other activities
- BioMérieux, Independent Member of the Board of Directors
- Fondation Mérieux, Chair of the Scientific Advisory Board[https://www.fondation-merieux.org/en/governance/ Governance] Fondation Mérieux.
- GISAID, Member of the Nomination Committee, Advisor{{Cite web|url=https://www.bloomberg.com/research/stocks/people/person.asp?personId=544622148&privcapId=771431|title=BioMerieux|website=www.bloomberg.com|access-date=2019-02-03}}{{Cite web |title=GISAID - Governance |url=https://gisaid.org/about-us/governance/ |access-date=2023-04-19 |website=gisaid.org |language=en}}{{Cite web|url=https://www.prnewswire.com/news-releases/groundbreaking-global-initiative-on-sharing-all-influenza-data-gisaid-celebrates-tenth-anniversary-300651619.html|title=Groundbreaking Global Initiative on Sharing All Influenza Data (GISAID) Celebrates Tenth Anniversary|website=www.prnewswire.com|language=en|access-date=2019-03-03}}
- Global Antibiotic Research and Development Partnership (GARDP), Member of the Board of Directors[https://gardp.org/team/ Board of Directors] Global Antibiotic Research and Development Partnership (GARDP).
- Joint Programming Initiative on Antimicrobial Resistance (JPIAMR), Member of the Management Board[https://www.jpiamr.eu/about/organisation/management-board/ Management Board] Joint Programming Initiative on Antimicrobial Resistance (JPIAMR).
- Solthis – Therapeutic Solidarity and Initiatives for Health, Member of the Board of Directors[https://www.solthis.org/en/the-board-of-directors/ Board of Directors] Solthis – Therapeutic Solidarity and Initiatives for Health.
- Vanke School of Public Health at Tsinghua University, Member of the International Advisory Board[https://vsph.tsinghua.edu.cn/en/gywm/International_Advisory_Board.htm Vanke School of Public Health: International Advisory Board] Tsinghua University.
- Wellcome Trust, Chair of the Strategic Advisory Board on Vaccines and Drug-resistant Infections[https://wellcome.ac.uk/what-we-do/our-work/vaccines-and-drug-resistant-infections-strategic-advisory-board Strategic Advisory Board on Vaccines and Drug-resistant Infections] Wellcome Trust.
- Wellcome Trust, Member of the Strategic Advisory Board on Innovation[https://wellcome.ac.uk/about-us/innovation-advisory-committee Strategic Advisory Board on Innovation] Wellcome Trust.
Awards
- 2017 Inserm International Prize.{{Cite web|url=https://www.inserm.fr/en/research-inserm/meet-our-researchers/inserm-prizes/marie-paule-kieny-2017-international-prize|title=Marie-Paule Kieny, 2017 International Prize|website=Inserm - From science to health|language=en-us|access-date=2019-02-03}}
- 1994 Prix Génération 2000-Impact Médecin{{Cite web|title=DNDi Board Chair, Dr Marie-Paule Kieny|url=https://dndi.org/our-people/marie-paule-kieny/}}
- 1991 Prix de l'Innovation Rhône-Poulenc
Decorations
- 2021 Officier de l'Ordre national du Mérite (chevalier in 2000)
- 2016 Chevalier de la Legion d'honneur.{{Cite web|title=Marie-Paule Kieny, décorée Chevalier de la Légion d'Honneur|url=https://onu-geneve.delegfrance.org/Marie-Paule-Kieny-decoree-Chevalier-de-la-Legion-d-Honneur|access-date=2019-02-03|website=Mission de la France|language=fr}}{{Dead link|date=February 2021|bot=InternetArchiveBot|fix-attempted=yes}}
References
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Category:University of Montpellier alumni
Category:University of Strasbourg alumni
Category:French women biologists