Mark Borodovsky
{{Short description|American biologist}}
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| fields = Bioinformatics
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| education = Moscow Institute of Physics and Technology
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| known_for = GeneMark
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| awards = ISCB Fellow (2020)
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Mark Borodovsky ({{langx|ru|Марк Бородовский}}) is a Regents' Professor at the Join Wallace H. Coulter Department of Biomedical Engineering of Georgia Institute of Technology and Emory University and Director of the Center for Bioinformatics and Computational Genomics at Georgia Tech.[http://www.bme.gatech.edu/facultystaff/faculty_record.php?id=36 Mark Borodovsky homepage at BME] He has also been a Chair of the Department of Bioinformatics at the Moscow Institute of Physics and Technology in Moscow, Russia from 2012 to 2022.
Borodovsky is a Founder of the Georgia Tech graduate Program in Bioinformatics (M.Sc. and Ph.D.), a Member of Educational Committee of the International Society of Computational Biology, as well as organizer of eleven International Conferences in Bioinformatics held at Georgia Tech starting 1997.
Research
Borodovsky started research in Bioinformatics at the Institute of Molecular Genetics USSR Academy of Sciences in 1985. In 1986 he introduced use of inhomogeneous Markov chain models for efficient modeling of protein-coding regions; this approach became a standard feature of gene finding algorithms. In 1990 he established a bioinformatics lab at Georgia Institute of Technology in Atlanta. Borodovsky has made many contributions in the area of development of gene finding algorithms, notably the GeneMark program (1993) that made an impact in the field and was used for annotation of the first completely sequenced genomes of Haemophilus influenzae and Methanococcus jannaschii. First hand experience in a number of genome projects motivated further development of advanced algorithms applicable to viral, prokaryotic, eukaryotic genomes and metagenomes.[http://topaz.gatech.edu/GeneMark/ Mark Borodovsky research homepage] These algorithms are currently in use in many research labs in the US and abroad as well as at the major sequencing and annotation centers, such as the Broad Institute, DOE Joint Genome Institute and NIH National Center for Biotechnology Information.
Education
Borodovsky received his Master of Science in Physics and Operation Research and PhD in Applied Mathematics (1976){{cite web |last1=Borodovsky |first1=Mark |title=Mark Borodovsky.Ph.D. |url=http://exon.gatech.edu/genemark/GTconferences/conference99/borodovsky.html |website=The Second Georgia Tech International Conference on Bioinformatics |access-date=1 July 2023}} from the Moscow Institute of Physics and Technology.
Honours
Borodovsky was elected a Fellow of the International Society for Computational Biology in 2020.{{cite web |title=February 19, 2020: ISCB Congratulates and Introduces the 2020 Class of Fellows! |url=https://www.iscb.org/iscb-news-items/4250-2020-feb19-iscb-congratulates-2020-class-fellows |website=www.iscb.org |accessdate=23 June 2020}}
References
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External links
- [http://genome.cshlp.org/content/18/12/1979 Gene prediction in novel fungal genomes using an ab initio algorithm with unsupervised training], Genome Research
- [https://web.archive.org/web/20051231122323/http://nar.oxfordjournals.org/cgi/content/full/33/20/6494 Gene identification in novel eukaryotic genomes by self-training algorithm], Nucleic Acids Research
- [https://web.archive.org/web/20060815013119/http://nar.oxfordjournals.org/cgi/content/full/33/suppl_2/W451 GeneMark: web software for gene finding in prokaryotes, eukaryotes and viruses] Nucleic Acids Research
- [https://web.archive.org/web/20051104145655/http://nar.oxfordjournals.org/cgi/content/abstract/29/12/2607 GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions], Nucleic Acids Research
- [https://web.archive.org/web/20051129111653/http://nar.oxfordjournals.org/cgi/content/full/27/19/3911 Heuristic approach to deriving models for gene finding], Nucleic Acids Research
- [https://archive.today/20130415161900/http://nar.oxfordjournals.org/cgi/content/full/26/4/1107 GeneMark.hmm: new solutions for gene finding], Nucleic Acids Research
- [https://web.archive.org/web/20140223100603/http://topaz.gatech.edu/GeneMark/PAPERS/GeneMark_parallel_gene___Article.pdf GenMark: Parallel Gene recognition for Both DNA Strands] Computers and Chemistry
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{{ISCB Fellows}}
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Category:Year of birth missing (living people)
Category:Moscow Institute of Physics and Technology alumni