Mark Henkelman

Henkelman obtained a Master of Science degree in theoretical physics at McMaster University, followed by a PhD exploring the use of electron microscopy, under the supervision of Peter Ottensmeyer, at the University of Toronto.{{Cite web|url=http://www.sickkids.ca/AboutSickKids/Newsroom/Past-News/2010/killam-prize.html|title=Henkelman to receive 2010 Killam Prize in health sciences|last=Children|first=The Hospital for Sick|website=www.sickkids.ca|language=en|access-date=1 January 2020}}{{Cite web|url=https://www.comp-ocpm.ca/download.php?id=324|title=Mark Henkelman awarded Canada Research Chair|last=Bronskill|first=Michael|date=2 April 2001|website=Canadian Medical Physics Newsletter|archive-url=|archive-date=|access-date=1 January 2020}}

The Ontario provincial government granted the Princess Margaret Hospital (now known as the Princess Margaret Cancer Centre) funding to purchase the first magnetic resonance imaging (MRI) scanner in Canada in 1982, making Henkelman one of the first to use and engage in MRI research in Canada, where he studied MRI image artifacts and developed image-guided surgery techniques, and used MRI in disease settings, such as cancer and neurosurgery. Henkelman then served as the vice-president of research at the Sunnybrook Health Science Centre before returning to the laboratory, and later in 2001, left to found a mouse imaging centre.{{Cite news|url=https://www.theglobeandmail.com/life/cancer-treatment-promising-if-youre-a-mouse/article18422087/|title=Cancer treatment promising, if you're a mouse|access-date=1 January 2020}}

Henkelman was the director of the Toronto Centre for Phenogenomics' (TCP) Mouse Imaging Centre (MICe), where MICe uses digital imaging technologies to characterize mouse models of different human diseases.{{Cite web|url=https://archive.macleans.ca/article/2007/10/22/the-mouse-house|title=THE MOUSE HOUSE {{!}} Maclean's {{!}} 22 OCT. 2007|last=TAYLOR|first=SUZANNE|website=Maclean's {{!}} The Complete Archive|language=en-US|access-date=1 January 2020}} For example, Henkelman supervised then postdoctoral fellow, Jacob Ellegood (now a research associate at MICe), who partnered with Jason P. Lerch (an associate professor at the University of Toronto, and a MICe principal investigator), to scan mice with magnetic resonance imaging, specifically those with Autism Spectrum Disorder.{{Cite journal|last=Damadian|first=Raymond V|date=January 1997|title=5606970 Multiple patient scanning on a magnetic resonance imaging apparatus|journal=Magnetic Resonance Imaging|volume=15|issue=5|pages=XIII|doi=10.1016/s0730-725x(97)89749-4|issn=0730-725X}}{{Cite web|url=https://www.uleth.ca/artsci/physics-astronomy/alumni-stories-0|title=Alumni Stories {{!}} University of Lethbridge|website=www.uleth.ca|access-date=1 January 2020}}

Henkelman was appointed a Canada Research Chair in Imaging Technologies in Human Diseases and Preclinical Model Cluster in 2008. He was a professor emeritus at the University of Toronto's Department of Medical Biophysics, and a senior scientist emeritus at The Hospital for Sick Children.

Henkelman's publications has been cited over 38,000 times, and has an h-index and i10-index of 98 and 327 respectively.{{Cite web|url=https://scholar.google.com/citations?user=fO2McaEAAAAJ&hl=en|title=Mark Henkelman – Google Scholar Citations|website=scholar.google.com|access-date=1 January 2020}} He has received the Robert L. Noble Prize in 2008, the Izaak Walton Killam Memorial Prize in 2010, the Gold Medal of the International Society of Magnetic Resonance in Medicine in 1998, and was appointed a Fellow of the Royal Society of Canada in 2005, and an Officer of the Order of Canada in 2019.{{Cite web|url=https://www.gg.ca/en/media/news/2019/governor-general-announces-120-new-appointments-order-canada|title=Governor General Announces 120 New Appointments to the Order of Canada|last=General|first=Office of the Secretary to the Governor|date=20 December 2019|website=The Governor General of Canada|access-date=1 January 2020}}{{Cite web|url=https://www.utoronto.ca/news/u-t-faculty-alumni-and-other-members-university-community-named-order-canada|title=U of T faculty, alumni and other members of university community named to Order of Canada|website=University of Toronto News|language=en|access-date=1 January 2020}}{{Cite journal|last=Association|first=Canadian Medical|date=18 May 2010|title=Briefly|journal=CMAJ|language=en|volume=182|issue=8|pages=E344–E346|doi=10.1503/cmaj.109-3234|issn=0820-3946|doi-access=free|pmc=2871237}}{{Cite web|url=http://www.everythingzoomer.com/arts-entertainment/stars-royals/2010/04/13/five-scholars-awarded-100000-killam-prize/|title=Five Scholars Awarded $100,000 Killam Prize|website=www.everythingzoomer.com|language=en|access-date=1 January 2020}}

• Singh, Sheila K., Cynthia Hawkins, Ian D. Clarke, Jeremy A. Squire, Jane Bayani, Takuichiro Hide, R. Mark Henkelman, Michael D. Cusimano, and Peter B. Dirks. "Identification of human brain tumour initiating cells." Nature 432, no. 7015 (2004): 396.
• Stanisz, Greg J., Ewa E. Odrobina, Joseph Pun, Michael Escaravage, Simon J. Graham, Michael J. Bronskill, and R. Mark Henkelman. "T1, T2 relaxation and magnetization transfer in tissue at 3T." Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine 54, no. 3 (2005): 507-512.
• Henkelman, R. Mark. "Measurement of signal intensities in the presence of noise in MR images." Medical Physics 12, no. 2 (1985): 232-233.
• Henkelman, R. M., G. J. Stanisz, and S. J. Graham. "Magnetization transfer in MRI: a review." NMR in Biomedicine: An International Journal Devoted to the Development and Application of Magnetic Resonance In Vivo 14, no. 2 (2001): 57-64.
• Henkelman, R. Mark, Xuemei Huang, Qing‐San Xiang, G. J. Stanisz, Scott D. Swanson, and Michael J. Bronskill. "Quantitative interpretation of magnetization transfer." Magnetic resonance in medicine 29, no. 6 (1993): 759-766.

• List of companions of the Order of Canada
• Robert L. Noble Prize
• Izaak Walton Killam Memorial Prize

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Category:Members of the Order of Canada

Category:Canadian biophysicists

Category:Fellows of the Royal Society of Canada