Maurice Pechet

Pechet and his research partners are credited with the discovery of the Pechet Factor Deficiency (OMIM:169200), a genetic disorder causing an abnormal blood clotting defect in a sister, brother and mother. Pechet and his research partners suggested that these persons lack a clotting factor that plays a role in the first phase of coagulation, following the activation of factor IX but before the activation of factor X.{{cite web|title=OMIM Entry (169200): Pechet Factor Deficiency|url=http://www.omim.org/entry/169200|website=Online Mendelian Inheritance in Man® An Online Catalog of Human Genes and Genetic Disorder|publisher=OMIM®, Johns Hopkins University|accessdate=15 December 2015}}{{cite web|title=Pechet Factor Deficiency|url=http://ctdbase.org/detail.go?type=disease&acc=MESH%3AC566814|website=Comparative Toxicogenomics Database|publisher=MDI Biological Laboratory & NC State University|accessdate=15 December 2015}}{{cite web|title=National Library of Medicine - Medical Subject Headings: Pechet Factor Deficiency|url=https://www.nlm.nih.gov/cgi/mesh/2016/MB_cgi?field=uid&term=C566814|publisher=U.S. National Library of Medicine|accessdate=15 December 2015}}

Pechet has been widely published in leading medical journals, such as the New England Journal of Medicine,{{Cite journal|title=Response of Adult Patients with Osteomalacia to Treatment with Crystalline 1α-Hydroxy Vitamin D3 291:866-871 October 24, 1974|journal=New England Journal of Medicine|volume=291|issue=17|pages=866–871|author=Philippe Bordier, M.D., Maurice M. Pechet, M.D., Robert Hesse, Pierre Marie, and Howard Rasmussen, M.D.|publisher=The New England Journal of Medicine|doi=10.1056/NEJM197410242911702|pmid=4415589|year=1974}} the American Journal of Medicine,{{Cite journal|url=http://www.amjmed.com/article/0002-9343(74)90762-1/abstract|volume=57|pages=13–20|author=Maurice M. Pechet, M.D., Robert H. Hesse|title=Metabolic and clinical effects of pure crystalline 1α-hydroxyvitamin D3 and 1α,25-dihydroxyvitamin D3|journal=The American Journal of Medicine|doi=10.1016/0002-9343(74)90762-1|year=1974}}{{Cite journal|url=http://www.amjmed.com/article/0002-9343(67)90112-X/abstract|volume=43|issue=5|pages=696–710|author=Maurice M. Pechet, M.D., Eduardo Bobadilla, M.D., Evelyn L. Carroll, A.B., Robert H. Hesse|title=Regulation of bone resorption and formation|journal=The American Journal of Medicine|doi=10.1016/0002-9343(67)90112-X|pmid=6054839|year=1967}} the Journal of Clinical Investigation,{{Cite journal|title=METABOLIC STUDIES WITH A NEW SERIES OF 1,4-DIENE STEROIDS. II. EFFECTS IN NORMAL SUBJECTS OF PREDNISONE, PREDNISOLONE, AND 9α-FLUOROPREDNISOLONE, Published in Volume 38, Issue 4 (April, 1959)|journal=Journal of Clinical Investigation|volume=38|issue=4|pages=691–701|author=Maurice M. Pechet, Blair Bowers and Frederic C. Bartters|publisher=The Journal of Clinical Investigation|doi=10.1172/JCI103848|pmid=13641421|pmc=293209|year=1959}} and the Journal of Pediatrics.{{Cite journal|url=http://www.jpeds.com/article/S0022-3476(81)80951-1/abstract|volume=99|issue=1|pages=16–25|author1=M.D. Howard Rasmussen|author2=M.D. Maurice Pechet|journal=The Journal of Pediatrics|author3=M.D. Constantine Anast|author4=R.N. Alice Mazur|author5=M.D. Joseph Gertner|author6=M.D. Arthur E. Broadus|title=Long-term treatment of familial hypophosphatemic rickets with oral phosphate and 1α-hydroxyvitamin D3|pmid=6265614|year=1981|doi=10.1016/S0022-3476(81)80951-1}}

• Served as President of the Research Institute for Medicine & Chemistry, Cambridge, MA.
• Sat on Harvard Medical School's Board of Fellows.{{Cite web|url=http://hms.harvard.edu/public/news/bof.html|title=Harvard Medical School Board of Fellows|publisher=Harvard Medical School Website}}
• Sat on the Harvard University's Board of Tutors in Biochemical Sciences.{{Cite web|url=http://www.mcb.harvard.edu/undergradstudy/biochem/Tutors.asp|title=Board of Tutors in Biochemical Sciences|url-status=dead|archiveurl=https://web.archive.org/web/20100703072154/http://www.mcb.harvard.edu/UndergradStudy/Biochem/Tutors.asp|archivedate=2010-07-03}}
• Served as a Director Emeritus of Canadian Western Bank.{{Cite web|url=http://investing.businessweek.com/businessweek/research/stocks/people/person.asp?personId=6545599&ticker=CWB:CN&previousCapId=2755343&previousTitle=Boston%20Medical%20Investors,%20Inc.|title=Canadian Western Bank (CWB:TSX) Company Profile|publisher=BloombergBusinessweek}}{{dead link|date=April 2023|bot=medic}}{{cbignore|bot=medic}}
• Served as a Honorary Trustee of Immune Disease Institute, Inc.
• Sat as senior member of the Senior Common Room of Lowell House, at Harvard University.{{Cite web|url=http://news.harvard.edu/gazette/story/2011/10/a-look-inside-lowell-house/|title=A look inside: Lowell House, Defined by a Harvard family, creating a larger one|publisher=Harvard Gazette|date=2011-10-27}}

Pechet was married to artist and teacher Kitty Pechet. She continues to reside in Cambridge, Massachusetts.{{Citation needed|date=April 2018}}

Pechet donated to a wide range of philanthropic causes.

In 1960, he established the Pechet Foundation.{{Cite web|url=http://nccsdataweb.urban.org/orgs/profile/046059253?popup=1#overview|title=The National Center for Charitable Statistics (NCCS)|access-date=2011-01-05|archive-url=https://web.archive.org/web/20110725063506/http://nccsdataweb.urban.org/orgs/profile/046059253?popup=1#overview|archive-date=2011-07-25|url-status=dead}} The Pechet Foundation has given to scientific research, poverty alleviation, education, the arts, and environmental causes. The Foundation has made donations and provided grants to such organizations as the Golden Foundation for the Arts, the Earthwatch Institute, The Cambridge Family & Children's Service, The Young Audiences of Massachusetts,{{Cite web|url=http://www.yamass.org/commpart.htm|title=The Young Audiences of Massachusetts: Community Partners and Benefactors|url-status=dead|archiveurl=https://web.archive.org/web/20100718115356/http://www.yamass.org/commpart.htm|archivedate=2010-07-18}} The New Sector Alliance,{{Cite web|url=http://newsector.org/partners/investors.php|title=The New Sector Alliance: Current and past supporters of New Sector|url-status=dead|archiveurl=https://web.archive.org/web/20100712203903/http://www.newsector.org/partners/investors.php|archivedate=2010-07-12}} The Cambridge Center for Adult Education, The Breast Cancer Research Foundation, The Perkins School for the Blind, The Center for Blood Research (CBR), and the New England Conservatory.

Pechet was a Director Emeritus of the Canadian Western Bank.{{Citation needed|date=April 2018}}

{{reflist|2}}

• [http://www.annals.org/content/64/5/1159.3 Annals of Internal Medicine]
• [http://www.the-asci.org/data/profile.php?pid=43391&PHPSESSID=c5505qj43uce6ca0m9q2ha61m6 The American Society for Clinical Investigation]
• [http://maurice-pechet-foundation.idilogic.aidpage.com/maurice-pechet-foundation/ The Maurice Pechet Foundation]
• [https://books.google.com/books?id=OO9gKGZmKCUC&dq=Maurice+Pechet,+M.D.,+Phd.&pg=PA164 The Golden Helix: Inside Biotech Ventures]

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Category:Harvard Medical School faculty

Category:Harvard Medical School alumni

Category:Harvard University alumni

Category:Harvard University faculty

Category:1918 births

Category:2012 deaths

Category:Physicians from Saskatchewan

Category:20th-century American philanthropists

Category:Canadian emigrants to the United States