Mebhydrolin

{{Short description|Chemical compound}}

{{cs1 config|name-list-style=vanc}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 462100967

| IUPAC_name = 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole

| image = Mebhydrolin_structure.png

| tradename =

| Drugs.com = {{drugs.com|international|mebhydrolin}}

| pregnancy_category = Not established{{cite web|url=http://home.intekom.com/pharm/bayer/fabahist.html |title=FABAHISTIN 50 mg (Tablets) |date=September 1970 |access-date=2007-03-02 |work=South African Electronic Package Inserts |url-status=dead |archive-url=https://web.archive.org/web/20061017085802/http://home.intekom.com/pharm/bayer/fabahist.html |archive-date=October 17, 2006 }}

| routes_of_administration = Oral

|legal_status=Rx-only

| CAS_number_Ref = {{cascite|correct|CAS}}

| CAS_number = 524-81-2

| CAS_supplemental =
6153-33-9 (1,5-naphthalenedisulfonate salt){{cite web | url = https://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=diazoline | title = Diazoline | publisher = US National Institutes of Health, National Library of Medicine | access-date = 2007-03-02 | work = National Library of Medicine - Medical Subject Headings}}

| ATC_prefix = R06

| ATC_suffix = AX15

| PubChem = 22530

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 21129

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 9SUK9B7XVY

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D08161

| C=19 | H=20 | N=2

| chemical_formula_ref = {{cite web | url = http://www.chemindustry.com/chemicals/969111.html | title = Mebhydrolin chemical information | access-date = 2007-03-02 | work = PubChem}}

| smiles = CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = FQQIIPAOSKSOJM-UHFFFAOYSA-N

| synonyms = 9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate{{cite web | url = https://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=mebhydroline | title = Mebhydroline | publisher = US National Institutes of Health, National Library of Medicine | access-date = 2007-03-02 | work = National Library of Medicine - Medical Subject Headings}}

}}

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.{{cite journal |vauthors=Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK |title=Interaction between ethanol and antihistamines: 3. mebhydrolin |journal=Med. J. Aust. |volume=2 |issue=9 |pages=477–9 |date=October 1981 |doi=10.5694/j.1326-5377.1981.tb112944.x |pmid=6119605 |s2cid=11034501 }}