Meningioangiomatosis

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Meningioangiomatosis is a rare disease and tauopathy of the brain. It is characterized by a benign lesion of the leptomeninges usually involving the cerebral cortex, and by leptomeningeal and meningovascular proliferation.{{cite journal|last=Wiebe|first=S.|title=Meningioangiomatosis: A comprehensive analysis of clinical and laboratory features|journal=Brain|date=1 April 1999|volume=122|issue=4|pages=709–726|doi=10.1093/brain/122.4.709|pmid=10219783 |doi-access=free}} Often the patient will present with seizures. The disease may be either sporadic or associated with neurofibromatosis type 2. The lesion is usually focused in one place, though extremely rare multifocal cases have been reported in both adults and children.{{cite journal |vauthors=Jamil O, Ramkissoon S, Folkerth R, Smith E |title=Multifocal meningioangiomatosis in a 3-year-old patient |type=Case report |journal=Journal of Neurosurgery: Pediatrics |volume=10 |issue=6 |year=2012 |pages=486–9 |pmid=23020197 |pmc=3762590 |doi=10.3171/2012.9.PEDS1224}} Biopsy is usually necessary for diagnosis. Treatment conventionally involves surgical removal of the lesion.