Menthoxypropanediol
{{Chembox
| IUPACName = Menthoxypropanediol
| ImageFile = Menthoxypropanediol-2D-skeletal.png
| ImageFile_Ref = {{chemboximage|correct|??}}
| ImageSize = 244
| ImageName = Stereo skeletal formula of menthoxypropanediol ((1R,2S,5R)-5-meth,-2-prop,-yl)
|Section1={{Chembox Identifiers
| IUPHAR_ligand = 2463
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 207792-35-6
| CASNo1_Ref = {{cascite|correct|CAS}}
| CASNo1 = 87061-04-9
| CASNo1_Comment = (non-specific)
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = KD6TZ2QICH
| PubChem = 5362595
| PubChem1 = 16006278
| PubChem1_Comment = (2S,5R)-5-meth,-2-prop,-yl
| PubChem2 = 6850757
| PubChem2_Comment = (1R,2S,5R)-5-meth,-2-prop,-yl
| PubChem3 = 44467722
| PubChem3_Comment = (1S,2R,5S)-5-meth,-2-prop,-yl
| PubChem4 = 15195782
| PubChem4_Comment = (2S)-2-ol, (1R,2S,5R)-5-meth,-2-prop,-yl
| ChemSpiderID = 4515105
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID1 = 13136530
| ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID1_Comment = (2S,5R)-5-meth,-2-prop,-yl
| ChemSpiderID2 = 5254045
| ChemSpiderID2_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID2_Comment = (1R,2S,5R)-5-meth,-2-prop,-yl
| EINECS = 289-296-2
| MeSHName = 3-Menthoxypropane-1,2-diol
| SMILES = CC(C)C1CCC(C)CC1OCC(O)CO
| StdInChI = 1S/C13H26O3/c1-9(2)12-5-4-10(3)6-13(12)16-8-11(15)7-14/h9-15H,4-8H2,1-3H3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = MDVYIGJINBYKOM-UHFFFAOYSA-N
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
}}
|Section2={{Chembox Properties
| C=13 | H=26 | O=3
}}
}}
Menthoxypropanediol (also known as Cooling agent 10 [tradename of Takasago]), is a synthetic derivative of menthol. While the cooling strength of 3-(l-menthoxy)propane-1,2-diol is accepted as being about 20–25% that of menthol, it is also noted that "in a Vaseline ointment, 3-(l-menthoxy)propane-1,2-diol shows a cool feeling 2.0 to 2.5 times stronger than that of l-menthol". It is used in various cosmetic chemical concoctions.{{cite web |url=http://www.leffingwell.com/cooler_than_menthol.htm |title=Cooler Than Menthol |access-date=2008-06-14 |author=Leffingwell & Associates }}
References
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