Menthoxypropanediol

{{Chembox

| IUPACName = Menthoxypropanediol

| ImageFile = Menthoxypropanediol-2D-skeletal.png

| ImageFile_Ref = {{chemboximage|correct|??}}

| ImageSize = 244

| ImageName = Stereo skeletal formula of menthoxypropanediol ((1R,2S,5R)-5-meth,-2-prop,-yl)

|Section1={{Chembox Identifiers

| IUPHAR_ligand = 2463

| CASNo_Ref = {{cascite|correct|CAS}}

| CASNo = 207792-35-6

| CASNo1_Ref = {{cascite|correct|CAS}}

| CASNo1 = 87061-04-9

| CASNo1_Comment = (non-specific)

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = KD6TZ2QICH

| PubChem = 5362595

| PubChem1 = 16006278

| PubChem1_Comment = (2S,5R)-5-meth,-2-prop,-yl

| PubChem2 = 6850757

| PubChem2_Comment = (1R,2S,5R)-5-meth,-2-prop,-yl

| PubChem3 = 44467722

| PubChem3_Comment = (1S,2R,5S)-5-meth,-2-prop,-yl

| PubChem4 = 15195782

| PubChem4_Comment = (2S)-2-ol, (1R,2S,5R)-5-meth,-2-prop,-yl

| ChemSpiderID = 4515105

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID1 = 13136530

| ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID1_Comment = (2S,5R)-5-meth,-2-prop,-yl

| ChemSpiderID2 = 5254045

| ChemSpiderID2_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID2_Comment = (1R,2S,5R)-5-meth,-2-prop,-yl

| EINECS = 289-296-2

| MeSHName = 3-Menthoxypropane-1,2-diol

| SMILES = CC(C)C1CCC(C)CC1OCC(O)CO

| StdInChI = 1S/C13H26O3/c1-9(2)12-5-4-10(3)6-13(12)16-8-11(15)7-14/h9-15H,4-8H2,1-3H3

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = MDVYIGJINBYKOM-UHFFFAOYSA-N

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

}}

|Section2={{Chembox Properties

| C=13 | H=26 | O=3

}}

}}

Menthoxypropanediol (also known as Cooling agent 10 [tradename of Takasago]), is a synthetic derivative of menthol. While the cooling strength of 3-(l-menthoxy)propane-1,2-diol is accepted as being about 20–25% that of menthol, it is also noted that "in a Vaseline ointment, 3-(l-menthoxy)propane-1,2-diol shows a cool feeling 2.0 to 2.5 times stronger than that of l-menthol". It is used in various cosmetic chemical concoctions.{{cite web |url=http://www.leffingwell.com/cooler_than_menthol.htm |title=Cooler Than Menthol |access-date=2008-06-14 |author=Leffingwell & Associates }}

References