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Merbecovirus

{{Short description|Subgenus of viruses}}

{{Virusbox

| image = Temi_a_1624482_f0001_oc.jpg

| image_alt = MERS-CoV: structure, attachment, viral entry, and genomic composition

| image_caption = MERS-CoV: structure, attachment, viral entry, and genomic composition

| taxon = Merbecovirus

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Merbecovirus is a subgenus of viruses in the genus Betacoronavirus, including the human pathogen Middle East respiratory syndrome–related coronavirus (MERS-CoV).{{cite web |title=Virus Taxonomy: 2018 Release |url=https://ictv.global/taxonomy |website=International Committee on Taxonomy of Viruses (ICTV) |accessdate=24 January 2019 |language=en |date=October 2018}} The viruses in this subgenus were previously known as group 2c coronaviruses.{{Cite journal|last1=Woo|first1=Patrick C. Y.|last2=Wang|first2=Ming|last3=Lau|first3=Susanna K. P.|last4=Xu|first4=Huifang|last5=Poon|first5=Rosana W. S.|last6=Guo|first6=Rongtong|last7=Wong|first7=Beatrice H. L.|last8=Gao|first8=Kai|last9=Tsoi|first9=Hoi-wah|last10=Huang|first10=Yi|last11=Li|first11=Kenneth S. M.|date=February 2007|title=Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features|journal=Journal of Virology|volume=81|issue=4|pages=1574–1585|doi=10.1128/JVI.02182-06|issn=0022-538X|pmc=1797546|pmid=17121802|quote=See figure 2.}}{{Cite journal|last1=Wong|first1=Antonio C. P.|last2=Li|first2=Xin|last3=Lau|first3=Susanna K. P.|last4=Woo|first4=Patrick C. Y.|date=2019-02-20|title=Global Epidemiology of Bat Coronaviruses|journal=Viruses|volume=11|issue=2|pages=174|doi=10.3390/v11020174|issn=1999-4915|pmc=6409556|pmid=30791586|quote=CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2].|doi-access=free}}

Taxonomy

The subgenus contains the following species, listed by scientific name and followed by the exemplar virus of the species:{{cite web|title=Virus Taxonomy: 2024 Release|url=https://ictv.global/taxonomy|publisher=International Committee on Taxonomy of Viruses|access-date=9 April 2025}}{{cite web |title=Species List: Coronaviridae |url=https://ictv.global/report/chapter/coronaviridae/taxonomy/coronaviridae |publisher=International Committee on Taxonomy of Viruses |access-date=9 April 2025}}

Structure

The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored.{{Citation|last1=Lai|first1=Michael M. C.|title=The Molecular Biology of Coronaviruses; III. Structure of Virions; A. Virion Morphology|date=1997-01-01|journal=Advances in Virus Research|volume=48|pages=5–6|editor-last=Maramorosch|editor-first=Karl|publisher=Academic Press|language=en|last2=Cavanagh|first2=David|doi=10.1016/S0065-3527(08)60286-9|pmid=9233431|pmc=7130985|editor2-last=Murphy|editor2-first=Frederick A.|editor3-last=Shatkin|editor3-first=Aaron J.}}{{Cite journal|last1=Woo|first1=Patrick C. Y.|last2=Huang|first2=Yi|last3=Lau|first3=Susanna K. P.|last4=Yuen|first4=Kwok-Yung|date=2010-08-24|title=Coronavirus Genomics and Bioinformatics Analysis|journal=Viruses|volume=2|issue=8|pages=1804–1820|doi=10.3390/v2081803|issn=1999-4915|pmc=3185738|pmid=21994708|quote=The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.|doi-access=free}}

See also

References

{{Reflist|30em}}

{{Coronaviridae}}

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Category:Virus subgenera

Category:Betacoronaviruses

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