Methestrol dipropionate
{{Short description|Chemical compound}}
{{Drugbox
| Verifiedfields =
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| verifiedrevid =
| IUPAC_name = [2-methyl-4-[4-(3-methyl-4-propanoyloxyphenyl)hexan-3-yl]phenyl] propanoate
| image = Methestrol dipropionate.svg
| width = 250px
| tradename = Meprane Dipropionate
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| class = Nonsteroidal estrogen; Estrogen ester
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| CAS_number_Ref =
| CAS_number = 130-73-4
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| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 199O25Z2BQ
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| PubChem = 6765
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| ChemSpiderID_Ref =
| ChemSpiderID = 6507
| synonyms = Methoestrol dipropionate; Metestrol dipropionate; Promethestrol dipropionate; Promethoestrol dipropionate; Dimethylhexestrol dipropionate
| C=26 | H=34 | O=4
| SMILES = CCC(C1=CC(=C(C=C1)OC(=O)CC)C)C(CC)C2=CC(=C(C=C2)OC(=O)CC)C
| StdInChI = 1S/C26H34O4/c1-7-21(19-11-13-23(17(5)15-19)29-25(27)9-3)22(8-2)20-12-14-24(18(6)16-20)30-26(28)10-4/h11-16,21-22H,7-10H2,1-6H3
| StdInChIKey = ORHVFDBDWJTZIN-UHFFFAOYSA-N
}}
Methestrol dipropionate or methoestrol dipropionate (brand name Meprane Dipropionate), also known as promethestrol dipropionate or promethoestrol dipropionate or as dimethylhexestrol dipropionate, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that is or was used clinically.{{cite book| vauthors = Ganellin CR, Triggle DJ |title=Dictionary of Pharmacological Agents |url= https://books.google.com/books?id=Z_mfTTIApVEC&pg=PA608|date=21 November 1996|publisher=CRC Press|isbn=978-0-412-46630-4|pages=608–}}{{cite book| vauthors = Brucker MC, King TL |title=Pharmacology for Women's Health|url=https://books.google.com/books?id=ofCeCgAAQBAJ&pg=PT640|date=8 September 2015|publisher=Jones & Bartlett Learning|isbn=978-1-284-10811-8|pages=640–}}{{cite book| vauthors = Ganellin CR, Triggle DJ |title=Dictionary of Pharmacological Agents|url=https://books.google.com/books?id=A0THacd46ZsC&pg=PA1298|date=21 November 1996|publisher=Taylor & Francis|isbn=978-0-412-46630-4|pages=1298–}}{{cite book| vauthors = Thomas JA, Keenan EJ |title=Principles of Endocrine Pharmacology|url=https://books.google.com/books?id=mTagBQAAQBAJ&pg=PA150|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-1-4684-5036-1|pages=150–}}{{cite book | vauthors = Prasad A, Sinha AK |title=Essential of Endocrinology and Reproductive Physiology|year=1985|url=https://books.google.com/books?id=sKOwvts4me8C&pg=PA85|publisher=Allied Publishers|pages=85–|id=GGKEY:HLNJ1BHUKW2}}{{cite book| vauthors = Modell W |title=Drugs in Current Use 1958|url=https://books.google.com/books?id=v2vwCAAAQBAJ&pg=PA114|date=21 November 2013|publisher=Springer|isbn=978-3-662-40303-7|pages=114–}}{{cite book| vauthors = Dubin WR, Stolberg R |title=Emergency Psychiatry for the House Officer|url=https://books.google.com/books?id=IwboCAAAQBAJ&pg=PT155|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-6690-4|pages=155–}}{{cite book| vauthors = Raspé G |title=Hormones and Embryonic Development: Advances in The Biosciences|url=https://books.google.com/books?id=Xp3pAgAAQBAJ&pg=PA141|date=22 October 2013|publisher=Elsevier Science|isbn=978-1-4831-5171-7|pages=141–}} It is the dipropionate form of methestrol (or promethestrol), which, in contrast to methestrol dipropionate, was never marketed.
See also
References
{{Reflist|2}}
{{Estrogens and antiestrogens}}
{{Estrogen receptor modulators}}
{{genito-urinary-drug-stub}}