Methotrexate-induced papular eruption

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Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 181. {{ISBN|0-7216-2921-0}}.

It has been suggested that it may represent a cutaneous small-vessel vasculitis.{{cite journal | doi = 10.1345/aph.1K271 | pmid = 18094347 | volume=42 | issue=1 | title=Methotrexate-induced papular eruption following treatment of psoriasis |date=January 2008 |vauthors=Mebazaa A, Kenani N, Denguezli M, etal | journal=Ann Pharmacother | pages=138–41}}