Michael Green (biologist)
{{Short description|American biologist (1954–2023)}}
{{Infobox scientist
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| name = Michael Green
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| birth_date = {{birth date|1954|01|20}}
| birth_place = Philadelphia, Pennsylvania, U.S.
| death_date = {{death date and age|2023|02|10|1954|01|20}}
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| fields = Cell biology, molecular biology
| workplaces = University of Massachusetts Medical School
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| alma_mater = University of Wisconsin–Madison, Washington University in St. Louis
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| doctoral_advisor = Robert G. Roeder
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| notable_students = Phil Zamore
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Michael Green (January 20, 1954 – February 10, 2023) was an American molecular biologist and cell biologist at the University of Massachusetts Medical School, where he was the chair of the Department of Molecular, Cell and Cancer Biology, director of the UMass Cancer Center, and a Howard Hughes Medical Institute investigator.{{cite web|title=Michael Green|url=https://profiles.umassmed.edu/display/132099|website=UMass Profiles|accessdate=12 April 2017}}{{cite web|title=Michael Green appointed director of UMass Cancer Center|url=http://www.umassmed.edu/news/news-archives/2015/04/michael-green-appointed-director-of-umass-cancer-center/|website=UMass Med Now|accessdate=12 April 2017|date=29 April 2015}} Green was a member of the National Academy of Sciences and the National Academy of Medicine.{{cite web|last1=Larson|first1=Lisa M.|title=Michael Green elected to National Academy of Sciences|url=http://www.umassmed.edu/news/news-archives/2014/04/michael-green-elected-to-national-academy-of-sciences/|website=UMass Med Now|accessdate=12 April 2017|date=30 April 2014}}{{cite web|last1=Larson|first1=Lisa M.|title=Michael Green elected to National Academy of Medicine|url=http://www.massachusetts.edu/news/featured-stories/michael-green-elected-national-academy-medicine|website=University of Massachusetts News|accessdate=12 April 2017|date=19 October 2015}}
Education and academic career
Green received his bachelor's degree in biochemistry from the University of Wisconsin–Madison.{{cite web|title=Michael Green|url=http://www.hhmi.org/scientists/michael-r-green|website=Howard Hughes Medical Institute|accessdate=12 April 2017}} He then went on to Washington University School of Medicine, from which he graduated in 1981 with his M.D. and Ph.D. in biochemistry under the supervision of Robert G. Roeder. He worked as a postdoctoral fellow with Thomas Maniatis, then at Harvard University, before joining the faculty there in 1984. He moved from Harvard to the University of Massachusetts Medical School in 1990 and remained there until his death in 2023. He was the chair of the Department of Molecular, Cell and Cancer Biology and was named the director of the UMass Cancer Center in 2015.
Green became a Howard Hughes Medical Institute investigator in 1994. He was elected to the National Academy of Sciences in 2014 and to the National Academy of Medicine in 2015.
Green was a co-founder of a Cambridge, Massachusetts-based biotechnology company called Fulcrum Therapeutics.{{cite web|title=Founders|url=http://www.fulcrumtx.com/founders/|website=Fulcrum Therapeutics|accessdate=12 April 2017}}
Research
Research in Green's laboratory focused on gene regulation, particularly on the regulation of gene transcription and of RNA splicing. The group also studies the effects of regulatory patterns on the behavior of cancer cells, using genome-wide RNA interference screens to identify genes involved in cell proliferation or apoptosis in the context of oncogenic mutations. In 2014, Green began studying the rare genetic disease Rett syndrome.{{cite web|last1=Larson|first1=Lisa M.|last2=Goodchild|first2=Bryan|title=UMMS scientist aiding a mother's quest for rare disease cure|url=http://www.umassmed.edu/news/news-archives/2014/05/UMMS-scientist-aiding-a-mothers-quest-for-rare-disease-cure/|website=UMass Med Now|accessdate=12 April 2017|date=7 May 2014}}
Death
Green died on February 10, 2023, at the age of 69.[https://www.telegram.com/obituaries/pneo0429433 Michael R. Green, MD, PhD]{{cite web|url=https://www.wbjournal.com/article/umass-chan-professor-vice-provost-for-research-dies-unexpectedly|title=UMass Chan professor, vice provost for research dies unexpectedly|work=Worcester Business Journal|first=Isabel|last=Tehan|date=13 February 2023|access-date=13 February 2023}}
References
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Category:American cell biologists
Category:American molecular biologists
Category:University of Wisconsin–Madison College of Agricultural and Life Sciences alumni
Category:Washington University School of Medicine alumni
Category:University of Massachusetts Amherst faculty
Category:Members of the United States National Academy of Sciences