Michelle Hampson

Hampson studied computer science at the University of Alberta.{{Cite web|title=Michelle Hampson, PhD|url=https://medicine.yale.edu/diagnosticradiology/profile/michelle_hampson/?tab=research|access-date=2021-07-11|website=medicine.yale.edu|language=en}} She moved to Boston University for her doctoral research, working on the computational modelling of neural networks. Hampson joined Yale University as a postdoctoral researcher. Her postdoctoral research involved some of the first studies of the functional connectivity in the resting state.{{Cite journal |last1=Hampson |first1=Michelle |last2=Peterson |first2=Bradley S. |last3=Skudlarski |first3=Pawel |last4=Gatenby |first4=J. Christopher |last5=Gore |first5=John C. |title=Detection of functional connectivity using temporal correlations in MR images |journal=Human Brain Mapping |volume=15 |issue=4 |pages=247–262 |date=2002 |doi=10.1002/hbm.10022 |url=https://doi.org/10.1002/hbm.10022 |language=en|pmc=6872035 }}{{Cite journal |last1=Hampson |first1=Michelle |last2=Driesen |first2=Naomi R. |last3=Skudlarski |first3=Pawel |last4=Gore |first4=John C. |last5=Constable |first5=R. Todd |title=Brain connectivity related to working memory performance |journal=The Journal of Neuroscience |volume=26 |issue=51 |pages=13338–13343 |date=2006-12-20 |doi=10.1523/JNEUROSCI.3408-06.2006 |url=https://doi.org/10.1523/JNEUROSCI.3408-06.2006 |language=en|pmc=2677699 }}{{Cite journal |last1=Hampson |first1=Michelle |last2=Tokoglu |first2=Fuyuze |last3=Sun |first3=Zhongdong |last4=Schafer |first4=Robin J. |last5=Skudlarski |first5=Pawel |last6=Gore |first6=John C. |last7=Constable |first7=R. Todd |title=Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca’s area varies with reading ability |journal=NeuroImage |volume=31 |issue=2 |pages=513–519 |date=2006-02-23 |doi=10.1016/j.neuroimage.2005.12.040 |url=https://doi.org/10.1016/j.neuroimage.2005.12.040 |language=en}}{{Cite journal |last1=Hampson |first1=Michelle |last2=Driesen |first2=Naomi R. |last3=Roth |first3=Jennifer K. |last4=Gore |first4=John C. |last5=Constable |first5=R. Todd |title=Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance |journal=The Journal of Neuroscience |volume=28 |issue=8 |pages=1051–1057 |date=2010 |doi=10.1016/j.mri.2010.03.021 |url=https://doi.org/10.1016/j.mri.2010.03.021 |language=en|pmc=2936669 }} She mapped the functional connectivity of the resting state to different behavioural variables. After her postdoc she started working with real time functional magnetic resonance imaging (fMRI). In particular, Hampson was interested in whether fMRI neurofeedback could be used to help people control their brain activity.{{Cite journal |last1=Hampson |first1=Michelle |last2=Tokoglu |first2=Fuyuze |last3=Sun |first3=Zhongdong |last4=Schafer |first4=Robin J. |last5=Skudlarski |first5=Pawel |last6=Gore |first6=John C. |last7=Constable |first7=R. Todd |title=Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca’s area varies with reading ability |journal=NeuroImage |volume=31 |issue=2 |pages=513–519 |date=2006-02-23 |doi=10.1016/j.neuroimage.2005.12.040 |url=https://doi.org/10.1016/j.neuroimage.2005.12.040 |language=en}}{{Cite journal |last1=Hampson |first1=Michelle |last2=Driesen |first2=Naomi R. |last3=Roth |first3=Jennifer K. |last4=Gore |first4=John C. |last5=Constable |first5=R. Todd |title=Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance |journal=The Journal of Neuroscience |volume=28 |issue=8 |pages=1051–1057 |date=2010 |doi=10.1016/j.mri.2010.03.021 |url=https://doi.org/10.1016/j.mri.2010.03.021 |language=en|pmc=2936669 }}{{Cite journal |last1=Hampson |first1=Michelle |last2=Driesen |first2=Naomi |last3=Roth |first3=Jennifer K. |last4=Gore |first4=John C. |last5=Constable |first5=R. Todd |title=Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance |journal=Magnetic Resonance Imaging |volume=28 |issue=8 |pages=1051–1057 |date=2010 |doi=10.1016/j.mri.2010.03.021 |url=https://doi.org/10.1016/j.mri.2010.03.021 |language=en|pmc=2936669 }}

Hampson was appointed to the faculty of Yale University in 2002, where she develops real-time (rt) fMRI for the treatment of mental and neurological conditions.{{Cite web |last1=Leigh |first1=Doug |last2=Watkins |first2=Ryan |last3=Hampson |first3=Michelle |title=Enduring Effects of Neurofeedback – Michelle Hampson |date=2019-10-15 |url=https://www.parsingscience.org/2019/10/15/michelle-hampson/ |website=Parsing Science |access-date=2021-07-11 |language=en-US}} The Hampson lab has worked on the development of fMRI neurofeedback to help people with obsessive–compulsive disorder, Tourette syndrome and post-traumatic stress disorder.{{Cite journal |last1=Scheinost |first1=Dustin |last2=Stoica |first2=Teodora |last3=Saksa |first3=Jason |last4=Papademetris |first4=Xenophon |last5=Constable |first5=Robert T. |last6=Pittenger |first6=Christopher |last7=Hampson |first7=Michelle |title=Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity |journal=Translational Psychiatry |volume=3 |pages=e250 |date=2013-04-30 |doi=10.1038/tp.2013.24 |url=https://doi.org/10.1038/tp.2013.24 |access-date=2025-04-08|pmc=3641411 }}{{Cite journal |last1=Sukhodolsky |first1=Denis G. |last2=Walsh |first2=Christopher |last3=Koller |first3=William N. |last4=Eilbott |first4=Jeffrey |last5=Rance |first5=Mariela |last6=Fulbright |first6=Robert K. |last7=Zhao |first7=Zhiying |last8=Bloch |first8=Michael H. |last9=King |first9=Robert |last10=Leckman |first10=James F. |last11=Scheinost |first11=Dustin |last12=Pittman |first12=Brian |last13=Hampson |first13=Michelle |title=Randomized, Sham-Controlled Trial of Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Tics in Adolescents With Tourette Syndrome |journal=Biological Psychiatry |volume=87 |issue=12 |pages=1063–1070 |date=2020-06-15 |doi=10.1016/j.biopsych.2019.07.035 |url=https://doi.org/10.1016/j.biopsych.2019.07.035 |access-date=2025-04-08|pmc=7015800 }}{{Cite journal |last1=Zhao |first1=Zhiying |last2=Duek |first2=Oded |last3=Seidemann |first3=Rachel |last4=Gordon |first4=Chelsea |last5=Walsh |first5=Christopher |last6=Romaker |first6=Emma |last7=Rance |first7=Mariela |last8=Koller |first8=William N. |last9=Harpaz-Rotem |first9=Ilan |last10=Hampson |first10=Michelle |title=Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial |journal=Translational Psychiatry |volume=13 |pages=177 |date=2023 |doi=10.1038/s41398-023-02467-6 |url=https://doi.org/10.1038/s41398-023-02467-6 |language=en|pmc=10209552 }}{{Cite journal |last1=Rance |first1=Mariela |last2=Zhao |first2=Zhiying |last3=Kichuk |first3=Stephen A. |last4=Romaker |first4=Emma |last5=Koller |first5=William N. |last6=Walsh |first6=Christopher |last7=Harris-Starling |first7=Cheyenne |last8=Wasylink |first8=Suzanne |last9=Adams Jr. |first9=Thomas |last10=Gruner |first10=Patricia |last11=Zaboski |first11=Brian |last12=Pittenger |first12=Christopher |last13=Hampson |first13=Michelle |title=Randomized clinical trial of fMRI neurofeedback for obsessive-compulsive disorder |journal=Psychiatry Research |volume=328 |pages=115458 |date=2023 |doi=10.1016/j.psychres.2023.115458 |url=https://doi.org/10.1016/j.psychres.2023.115458 |language=en|pmc=10695074 }}{{Cite journal |last1=Awasthi |first1=Jitendra |last2=Harris-Starling |first2=Cheyenne |last3=Kalvin |first3=Carla |last4=Pittman |first4=Brian |last5=Park |first5=Haesoo |last6=Bloch |first6=Michael |last7=Fernandez |first7=Thomas V. |last8=Sukhodolsky |first8=Denis G. |last9=Hampson |first9=Michelle |title=Protocol description for a randomized controlled trial of fMRI neurofeedback for tics in adolescents with Tourette Syndrome |journal=Psychiatry Research: Neuroimaging |volume=336 |pages=111692 |date=2023-07-22 |doi=10.1016/j.pscychresns.2023.111692 |url=https://doi.org/10.1016/j.pscychresns.2023.111692 |language=en|pmc=10722977 }}For example, in patients with contamination anxiety, making use of neurofeedback to visualize and control activity in the orbitofrontal cortex was shown to be helpful for controlling that anxiety.{{Cite web|last=Hathaway|first=Bill|date=2013-05-07|title=Research in the News: Real-time brain feedback can help people overcome anxiety|url=https://news.yale.edu/2013/05/07/research-news-real-time-brain-feedback-can-help-people-overcome-anxiety|access-date=2021-07-11|website=YaleNews|language=en}}{{Cite web|title=Embedded JoVE Video:Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety|url=https://www.jove.com/embed/player?id=3535&access=mcpkbdm5&t=1&a=1&s=1|access-date=2021-07-11|website=www.jove.com}} For patients with post-traumatic stress disorder, Hampson explored whether it is possible to control activity in the amygdala when recalling trauma.{{Cite journal |last1=Zhao |first1=Zhiying |last2=Duek |first2=Oded |last3=Seidemann |first3=Rachel |last4=Gordon |first4=Chelsea |last5=Walsh |first5=Christopher |last6=Romaker |first6=Emma |last7=Rance |first7=Mariela |last8=Koller |first8=William N. |last9=Harpaz-Rotem |first9=Ilan |last10=Hampson |first10=Michelle |title=Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial |journal=Translational Psychiatry |volume=13 |pages=177 |date=2023 |doi=10.1038/s41398-023-02467-6 |url=https://doi.org/10.1038/s41398-023-02467-6 |language=en|pmc=10209552 }} Her group found that clinical impacts of neurofeedback can take weeks to unfold after training.{{Cite journal |last1=Rance |first1=Mariela |last2=Walsh |first2=Christopher |last3=Sukhodolsky |first3=Denis G. |last4=Pittman |first4=Brian |last5=Qiu |first5=Maolin |last6=Kichuk |first6=Stephen A. |last7=Wasylink |first7=Suzanne |last8=Koller |first8=William N. |last9=Bloch |first9=Michael |last10=Gruner |first10=Patricia |last11=Scheinost |first11=Dustin |last12=Pittenger |first12=Christopher |last13=Hampson |first13=Michelle |title=Time course of clinical change following neurofeedback |journal=NeuroImage |volume=181 |pages=807–813 |date=2018-05-02 |doi=10.1016/j.neuroimage.2018.05.001 |url=https://doi.org/10.1016/j.neuroimage.2018.05.001 |language=en|pmc=6454268 }}

In 2021, Hampson wrote the Elsevier textbook fMRI Neurofeedback.{{Cite web|title=fMRI Neurofeedback - 1st Edition|url=https://www.elsevier.com/books/fmri-neurofeedback/hampson/978-0-12-822421-2|access-date=2021-07-11|website=www.elsevier.com}}

Most recently, she has become interested in ethical issues associated with neurofeedback.{{Cite book |last=Hampson |first=Michelle |title=fMRI Neurofeedback |chapter=Chapter 14: Ethical considerations for fMRI neurofeedback |publisher=Elsevier |location=London |date=2021 |isbn=978-0-12-822421-2 |doi=10.1016/B978-0-12-822421-2.00007-7 |url=https://doi.org/10.1016/B978-0-12-822421-2.00007-7}}{{Cite journal |last1=Furnari |first1=Fiona |last2=Park |first2=Haesoo |last3=Yaffe |first3=Gideon |last4=Hampson |first4=Michelle |title=Neurofeedback: potential for abuse and regulatory frameworks in the United States |journal=Philosophical Transactions of the Royal Society B |volume=379 |number=1897 |pages=20230099 |date=2024 |doi=10.1098/rstb.2023.0099 |url=https://doi.org/10.1098/rstb.2023.0099 |language=en|pmc=11513161 }}

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