Middle Branch Moose River

{{Use American English|date=February 2025}}

{{Infobox river

| name = Middle Branch Moose River

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| image = Middle Branch Moose River sign at Old Forge Route 28.jpg

| image_caption = Crossing Route 28 in Old Forge

| map =

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| pushpin_map = New York Adirondack Park#USA

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| pushpin_map_caption = Location of the mouth within New York

| subdivision_type1 = Country

| subdivision_name1 = United States

| subdivision_type2 = State

| subdivision_name2 = New York

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| source1 = First Lake

| source1_location = Old Forge, New York

| source1_coordinates= {{coord|43.7128453|-74.9698964|format=dms}}{{cite GNIS|957083|Middle Branch Moose River|May 25, 2020}}

| source1_elevation = {{convert|1706|ft}}{{cite GNIS|950106|First Lake|May 25, 2020}}

| mouth = Moose River

| mouth_location = Mckeever, New York

| mouth_coordinates = {{coord|43.6211795|-75.0773926|format=dms|display=inline,title}}

| mouth_elevation = {{convert|1512|ft|abbr=on}}

| progression =

| river_system =

| basin_size = {{convert|151|sqmi|abbr=on}}

| tributaries_left = Nelson Lake

| tributaries_right = North Branch Moose River

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Middle Branch Moose River starts in Old Forge, New York at the outlet of First Lake and flows into the Moose River in Mckeever, New York.{{cite web

| url = https://waterdata.usgs.gov/nwis/inventory/?site_no=04254000&agency_cd=USGS

| title = Middle Branch Moose River

| website = usgs.gov

| publisher = United States Geological Survey

| access-date = 22 April 2017}}