Mitochondrial thiamine pyrophosphate carrier
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene.{{cite journal | vauthors = Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F | title = Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC) | journal = Cytogenet Cell Genet | volume = 93 | issue = 1–2 | pages = 40–2 |date=Jul 2001 | pmid = 11474176 | doi =10.1159/000056945 | s2cid = 44985945 }}{{cite journal | vauthors = Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE | title = The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 5 | pages = 2284–8 |date=Mar 2001 | pmid = 11226231 | pmc = 30130 | doi = 10.1073/pnas.031430998 | bibcode = 2001PNAS...98.2284D | doi-access = free }}{{cite web | title = Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60386}}
See also
References
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Further reading
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- {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Rosenberg MJ, Agarwala R, Bouffard G, etal |title=Mutant deoxynucleotide carrier is associated with congenital microcephaly |journal=Nat. Genet. |volume=32 |issue= 1 |pages= 175–9 |year= 2002 |pmid= 12185364 |doi= 10.1038/ng948 |s2cid=23768596 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors= Carrisi C, Antonucci D, etal |title= Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1). |journal= Journal of Inorganic Biochemistry|volume=130 |pages= 28–31 |year= 2013 |pmid= 24148759 |doi= 10.1016/j.jinorgbio.2013.09.012}}
- {{cite journal |vauthors=Lam W, Chen C, Ruan S, etal |title=Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake |journal=Mol. Pharmacol. |volume=67 |issue= 2 |pages= 408–16 |year= 2005 |pmid= 15539640 |doi= 10.1124/mol.104.007120 |s2cid=25269301 }}
- {{cite journal |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 |doi-access= free }}
- {{cite journal |vauthors=Lindhurst MJ, Fiermonte G, Song S, etal |title=Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 43 |pages= 15927–32 |year= 2006 |pmid= 17035501 |doi= 10.1073/pnas.0607661103 | pmc=1595310 |bibcode=2006PNAS..10315927L |doi-access=free }}
- {{cite journal |vauthors=Iacopetta D, Carrisi C, et al. |title=The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster. |journal= FEBS J |volume=277 |pages= 1172–81 |year= 2010 |issue=5 |pmid=20121944 |doi= 10.1111/j.1742-4658.2009.07550.x |s2cid=24140143 |doi-access=free }}
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External links
- [https://www.ncbi.nlm.nih.gov/books/NBK1365/ GeneReviews/NCBI/NIH/UW entry on Amish Lethal Microcephaly]
- [https://www.ncbi.nlm.nih.gov/omim/220500,606521,607196,606521,607196 OMIM entries on Amish Lethal Microcephaly]
{{Membrane transport proteins}}
Category:Solute carrier family
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