Mohammad Islam Khan

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Born on the Christmas Eve of 1957,{{Cite web |url=http://mahascience.org/files/Fellowship/files/academyMembers.htm#k |title=MAS fellow |date=2017-12-06 |website=Maharashtra Academy of Sciences |access-date=2017-12-06}} Mohammad Islam Khan obtained an MSc in biotechnology in 1978 and joined the Indian Institute of Chemical Biology (IICB) as a faculty, simultaneously doing his doctoral research at the Indian Institute of Science which earned him a PhD in 1986 from Aligarh Muslim University.{{Cite web |url=http://www.niscair.res.in/sciencecommunication/RnDNewsLetters/csirnews2k3/csirnews_15june03.htm |title=National Biosciences Award to Dr M. I. Khan |date=15 June 2003 |website=Council of Scientific and Industrial Research |access-date=2017-12-05}} Moving to the US, he did his post-doctoral work at Albert Einstein College of Medicine during 1987–90 and on his return to India in 1990, he joined the National Chemical Laboratory (NCL) as a scientist where he spent the rest of his career, barring a stint at the University of Göttingen during 2000–01 as an overseas associate of the Department of Biotechnology. He was holding the post of a scientist at the Division of Biochemical Sciences of NCL when he died in November 2010, aged 53.{{Cite web |url=http://www.ncl-india.org/files/DisplayResource.aspx?ResourceId=6c5310e2-777a-4ed5-bc67-2022232ec273&OriginalFileName=frd87.pdf |title=Peptides for treating cancer |date=2017-12-05 |website=National Chemical Laboratory |access-date=2017-12-05}}

Khan was known for his contributions in the disciplines of glycobiology and nanobiotechnology with special focus on the biology of lectins. His work was known to have assisted in widening our understanding of cell adhesion. He demonstrated the role of yeast cell surface lectins in the adhesion of yeast cells which is also known as flocculation. He isolated Fusarium sporotrichioides from rose plant which has since been deposited by him at the National Collection of Industrial Microorganisms (NCIM), a government-funded microbial culture repository based at NCL.{{Cite web |url=http://www.ncl-india.org/files/NCIM/CatalogueDetails.aspx?NCIMNo=1330&menuid=ql4 |title=strain no. LR11 |date=2017-12-06 |website=National Collection of Industrial Microorganisms (NCIM) |access-date=2017-12-06}} The research team under his leadership was successful in isolating a peptide from Streptomyces that showed potency as an inhibitor of Cysteine proteases and the finding is reported to have use in the prophylaxis of cancer by preventing the migration of cancer cells.{{Cite journal |last=Jay Prakash Singh, Sudarsan Tamang, P. R. Rajamohanan, N. C. Jima, Goutam Chakraborty, Gopal C. Kundu, Sushma M. Gaikwad, Mohamad I. Khan |title=Isolation, Structure, and Functional Elucidation of a Modified Pentapeptide, Cysteine Protease Inhibitor (CPI-2081) from Streptomyces Species 2081 that Exhibit Inhibitory Effect on Cancer Cell Migration |journal=J. Med. Chem. |volume=53 |issue=14 |pages=5121–5128 |doi=10.1021/jm9014179|pmid=20552970 |year=2010 }} Towards the latter part of his career, he worked on the synthesis of metal‑metal sulphides/metal oxide nanoparticles using fungi and it was reported that the team synthesized the nano-particles outside a cell for the first time. His studies have been documented by way of a number of articles{{Refn|group=note|Please see Selected bibliography section}} and PubMed, an online article repository of scientific articles has listed several of them.{{Cite journal |title=Khan MI [Author] |journal=Biochemical Pharmacology |volume=24 |issue=20 |pages=1903–4 |date=2017-11-21 |pmid = 20|last1 = Barthel|first1 = W.|last2=Markwardt |first2=F. |doi=10.1016/0006-2952(75)90415-3}}

The Indian National Science Academy awarded Khan the INSA Young Scientist Medal in 1987.{{Cite web |url=http://insaindia.res.in/youngmedal.php |title=INSA Young Scientists Medal |date=2017-11-12 |publisher=Indian National Science Academy |access-date=2017-11-12 |archive-date=11 May 2021 |archive-url=https://web.archive.org/web/20210511084357/https://www.insaindia.res.in/youngmedal.php |url-status=dead }} Five years later, he received the 1992 Young Scientist Award of the Council of Scientific and Industrial Research. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2002. He also received the elected fellowships from three Indian science academies namely, the National Academy of Sciences, India, Muslim Association for the Advancement of Science and Maharashtra Academy of Sciences.

• {{Cite journal |last1=Shabab |first1=M. |last2=Kulkarni |first2=Mahesh J. |last3=Khan |first3=M. Islam |date=January 2008 |title=Study of papain-cystatin interaction by intensity fading MALDI-TOF-MS |journal=The Protein Journal |volume=27 |issue=1 |pages=7–12 |doi=10.1007/s10930-007-9102-3 |issn=1572-3887 |pmid=17763924|s2cid=29363617 }}
• {{Cite journal |last1=Sahasrabuddhe |first1=Anagh A. |last2=Gaikwad |first2=Sushama M. |last3=Krishnasastry |first3=M. V. |last4=Khan |first4=M. Islam |date=December 2004 |title=Studies on recombinant single chain Jacalin lectin reveal reduced affinity for saccharides despite normal folding like native Jacalin |journal=Protein Science |volume=13 |issue=12 |pages=3264–3273 |doi=10.1110/ps.04968804 |issn=0961-8368 |pmc=2287297 |pmid=15557267}}
• {{Cite journal |last1=Khan |first1=Md Idrish Raja |last2=Saha |first2=Ratan Kumar |last3=Saha |first3=Himadri |date=2017-11-25 |title=Muli bamboo (Melocanna baccifera) leaves ethanolic extract a non-toxic phyto-prophylactic against low pH stress and saprolegniasis in Labeo rohita fingerlings |journal=Fish & Shellfish Immunology |volume=74 |pages=609–619 |doi=10.1016/j.fsi.2017.11.047 |issn=1095-9947 |pmid=29183812|s2cid=3625451 }}

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• Nanoparticles
• Flocculation

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{{portal|India|Biology|Medicine}}

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• {{Cite web |url=http://lib.unipune.ac.in:8080/jspui/bitstream/123456789/445/4/04_acknowledgement.pdf |title=Acknowledgements - 1 |last=Madhura M. Gurjar |date=2017-12-06 |website=University of Pune |access-date=2017-12-06}}
• {{Cite web |url=http://shodhganga.inflibnet.ac.in/bitstream/10603/2611/9/09_acknowledgments.pdf |title=Acknowledgements - 2 |last=Aijaz Ahmad Wani |date=2017-12-06 |website=Shodh Ganga |access-date=2017-12-06}}
• {{Cite web |url=http://shodhganga.inflibnet.ac.in/bitstream/10603/2509/4/04_acknowledgement.pdf |title=Acknowledgements - 3 |last=Feroz Khan |date=2017-12-06 |website=Shodh Ganga |access-date=2017-12-06}}

{{N-BIOS Laureates 1999–2009}}

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{{DEFAULTSORT:Khan, Mohammad Islam}}

Category:N-BIOS Prize recipients

Category:Indian molecular biologists

Category:Fellows of the National Academy of Sciences, India

Category:Scientists from Pune

Category:Indian Institute of Science alumni

Category:Aligarh Muslim University alumni

Category:Albert Einstein College of Medicine alumni

Category:University of Göttingen

Category:1957 births

Category:2010 deaths

Category:Indian biochemists