Monocarboxylate transporter 5

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{{Short description|Protein-coding gene in the species Homo sapiens}}

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Monocarboxylate transporter 5 is a protein that in humans is encoded by the SLC16A4 gene.{{cite journal | vauthors = Price NT, Jackson VN, Halestrap AP | title = Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past | journal = The Biochemical Journal | volume = 329 | issue = 2 | pages = 321–8 | date = January 1998 | pmid = 9425115 | pmc = 1219047 | doi = 10.1042/bj3290321}}{{cite web | title = Entrez Gene: SLC16A4 solute carrier family 16, member 4 (monocarboxylic acid transporter 5)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9122}}

See also

References

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Further reading

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  • {{cite journal | vauthors = Halestrap AP, Price NT | title = The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation | journal = The Biochemical Journal | volume = 343 | issue = 2 | pages = 281–99 | date = October 1999 | pmid = 10510291 | pmc = 1220552 | doi = 10.1042/bj3430281 }}
  • {{cite journal | vauthors = Halestrap AP, Meredith D | title = The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond | journal = Pflügers Archiv | volume = 447 | issue = 5 | pages = 619–28 | date = February 2004 | pmid = 12739169 | doi = 10.1007/s00424-003-1067-2 | s2cid = 15498611 }}
  • {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = January 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
  • {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = October 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
  • {{cite journal | vauthors = Pilegaard H, Terzis G, Halestrap A, Juel C | title = Distribution of the lactate/H+ transporter isoforms MCT1 and MCT4 in human skeletal muscle | journal = The American Journal of Physiology | volume = 276 | issue = 5 Pt 1 | pages = E843-8 | date = May 1999 | doi = 10.1152/ajpendo.1999.276.5.E843 | pmid = 10329977 }}
  • {{cite journal | vauthors = Manning Fox JE, Meredith D, Halestrap AP | title = Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle | journal = The Journal of Physiology | volume = 529 | issue = 2 | pages = 285–93 | date = December 2000 | pmid = 11101640 | pmc = 2270204 | doi = 10.1111/j.1469-7793.2000.00285.x }}
  • {{cite journal | vauthors = Philp NJ, Wang D, Yoon H, Hjelmeland LM | title = Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells | journal = Investigative Ophthalmology & Visual Science | volume = 44 | issue = 4 | pages = 1716–21 | date = April 2003 | pmid = 12657613 | doi = 10.1167/iovs.02-0287 | doi-access = free }}
  • {{cite journal | vauthors = Juel C, Holten MK, Dela F | title = Effects of strength training on muscle lactate release and MCT1 and MCT4 content in healthy and type 2 diabetic humans | journal = The Journal of Physiology | volume = 556 | issue = Pt 1 | pages = 297–304 | date = April 2004 | pmid = 14724187 | pmc = 1664883 | doi = 10.1113/jphysiol.2003.058222 }}
  • {{cite journal | vauthors = Settle P, Mynett K, Speake P, Champion E, Doughty IM, Sibley CP, D'Souza SW, Glazier J | title = Polarized lactate transporter activity and expression in the syncytiotrophoblast of the term human placenta | journal = Placenta | volume = 25 | issue = 6 | pages = 496–504 | date = July 2004 | pmid = 15135232 | doi = 10.1016/j.placenta.2003.11.009 }}
  • {{cite journal | vauthors = Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP | title = Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70) | journal = The Journal of Biological Chemistry | volume = 280 | issue = 29 | pages = 27213–21 | date = July 2005 | pmid = 15917240 | doi = 10.1074/jbc.M411950200 | doi-access = free }}
  • {{cite journal | vauthors = Merezhinskaya N, Ogunwuyi SA, Fishbein WN | title = Expression of monocarboxylate transporter 4 in human platelets, leukocytes, and tissues assessed by antibodies raised against terminal versus pre-terminal peptides | journal = Molecular Genetics and Metabolism | volume = 87 | issue = 2 | pages = 152–61 | date = February 2006 | pmid = 16403666 | doi = 10.1016/j.ymgme.2005.09.029 | url = https://zenodo.org/record/1259485 }}
  • {{cite journal | vauthors = Bickham DC, Bentley DJ, Le Rossignol PF, Cameron-Smith D | title = The effects of short-term sprint training on MCT expression in moderately endurance-trained runners | journal = European Journal of Applied Physiology | volume = 96 | issue = 6 | pages = 636–43 | date = April 2006 | pmid = 16408234 | doi = 10.1007/s00421-005-0100-x | s2cid = 10354316 }}
  • {{cite journal | vauthors = Ullah MS, Davies AJ, Halestrap AP | title = The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism | journal = The Journal of Biological Chemistry | volume = 281 | issue = 14 | pages = 9030–7 | date = April 2006 | pmid = 16452478 | doi = 10.1074/jbc.M511397200 | doi-access = free }}
  • {{cite journal | vauthors = Bishop D, Edge J, Thomas C, Mercier J | title = High-intensity exercise acutely decreases the membrane content of MCT1 and MCT4 and buffer capacity in human skeletal muscle | journal = Journal of Applied Physiology | volume = 102 | issue = 2 | pages = 616–21 | date = February 2007 | pmid = 17082373 | doi = 10.1152/japplphysiol.00590.2006 | s2cid = 336956 | url = https://hal-insep.archives-ouvertes.fr/hal-01585662/document }}

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{{Membrane transport proteins}}

Category:Solute carrier family

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