Monogalactosyldiacylglycerol synthase

{{infobox enzyme

| Name = 1,2-diacylglycerol 3-beta-galactosyltransferase

| EC_number = 2.4.1.46

| CAS_number = 37277-55-7

| GO_code = 0046509

| image =

| width =

| caption =

}}

In enzymology, a monogalactosyldiacylglycerol synthase ({{EC number|2.4.1.46}}) is an enzyme that catalyzes the chemical reaction

:UDP-galactose + 1,2-diacyl-sn-glycerol $\rightleftharpoons$ UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol

Thus, the two substrates of this enzyme are UDP-galactose and 1,2-diacyl-sn-glycerol, whereas its two products are UDP and 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase. Other names in common use include uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase, UDP-galactose:diacylglycerol galactosyltransferase, MGDG synthase, UDP galactose-1,2-diacylglycerol galactosyltransferase, UDP-galactose-diacylglyceride galactosyltransferase, UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase, 1beta-MGDG, and 1,2-diacylglycerol 3-beta-galactosyltransferase. This enzyme participates in glycerolipid metabolism.

References

{{cite journal | author = Veerkamp JH | date = 1974 | title = Biochemical changes in Bifidobacterium bifidum var. pennsylvanicus after cell-wall inhibition. VI. Biosynthesis of the galactosyldiglycerides | journal = Biochim. Biophys. Acta | volume = 348 | pages = 23–34 | pmid = 4838219 | issue = 1 | doi = 10.1016/0005-2760(74)90089-7 }}
{{cite journal | vauthors = Wenger DA, Petitpas JW, Pieringer RA | date = 1968 | title = The metabolism of glyceride glycolipids. II. Biosynthesis of monogalactosyl diglyceride from uridine diphosphate galactose and diglyceride in brain | journal = Biochemistry | volume = 7 | pages = 3700–7 | pmid = 5681471 | doi = 10.1021/bi00850a049 | issue = 10 }}
{{cite journal | vauthors = K, Douce R, Joyard J | date = 1999 | title = Biochemical and topological properties of type A MGDG synthase, a spinach chloroplast envelope enzyme catalyzing the synthesis of both prokaryotic and eukaryotic MGDG | journal = Eur. J. Biochem. | volume = 265 | pages = 990–1001 | pmid = 10518794 | doi = 10.1046/j.1432-1327.1999.00801.x | issue = 3 | doi-access = free }}
{{cite journal | vauthors = Benning C, Ohta H | date = 2005 | title = Three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants | journal = J. Biol. Chem. | volume = 280 | pages = 2397–400 | pmid = 15590685 | doi = 10.1074/jbc.R400032200 | issue = 4 | doi-access = free }}

Category:EC 2.4.1

Category:Enzymes of unknown structure