Motile sperm domain containing 2

{{Short description|Protein-coding gene in the species Homo sapiens}}

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Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene.{{cite web | title = Entrez Gene: Motile sperm domain containing 2 | url = https://www.ncbi.nlm.nih.gov/gene/158747 }} It is an endoplasmic reticulum–resident protein involved in membrane contact site formation.{{cite journal | vauthors = Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F | title = Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites | journal = EMBO Reports | volume = 19 | issue = 7 | pages = e45453 | date = June 2018 | pmid = 29858488 | pmc = 6030701 | doi = 10.15252/embr.201745453 }} Its domain homologous to Major Sperm Protein (MSP domain) is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.

References

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Further reading

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  • {{cite journal | vauthors = Velez Edwards DR, Naj AC, Monda K, North KE, Neuhouser M, Magvanjav O, Kusimo I, Vitolins MZ, Manson JE, O'Sullivan MJ, Rampersaud E, Edwards TL | title = Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study | journal = Human Genetics | volume = 132 | issue = 3 | pages = 323–36 | date = March 2013 | pmid = 23192594 | pmc = 3704217 | doi = 10.1007/s00439-012-1246-3 }}

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