Motoric cognitive risk

{{Short description|Syndrome implying high risk of dementia}}

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Motoric cognitive risk (MCR) is a syndrome that has been defined as a pre-dementia state.Verghese J, Wang C, Lipton RB, Holtzer R. Motoric cognitive risk syndrome and the risk of dementia. Journals Gerontol - Ser A Biol Sci Med Sci. 2013;68(4):412-418. doi:10.1093/gerona/gls191 It is characterized by a measurable slow walking speed and self-reported cognitive complaints in the absence of significant functional impairment or dementia. The cognitive impairment is less than what would typically be detected on standard cognitive testing. The syndrome was first introduced by J. Verghese et al. in 2013.

MCR has been shown to reliably identify individuals at high risk.Mullin DS, Cockburn A, Welstead M, Luciano M, Russ TC, Muniz‐Terrera G. Mechanisms of motoric cognitive risk—Hypotheses based on a systematic review and meta‐analysis of longitudinal cohort studies of older adults. Alzheimer’s Dement. Published online February 9, 2022. doi:10.1002/ALZ.12547 MCR has potential for early identification and prevention of dementia.