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Mouse brain development timeline

{{short description|Developmental stage in mice}}

The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.

Stages in brain development

class="wikitable"
Width=3|Days post conception

! Event

! Reference

9

| cranial motor nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

10

| subplate -start of neurogenesis

| Bayer and Altman (1991)

10

| inferior olivary nucleus - peak of neurogenesis

| Finlay and Darlington (1995)

10.5

| retinal ganglion cell generation - start of neurogenesis

| Robinson and Dreher (1990)

10.5

| superficial superior colliculus (SC) laminae- start of neurogenesis

| Robinson and Dreher (1990)

10.5

| dorsal lateral geniculate nucleus (dLGN) - start of neurogenesis

| Robinson and Dreher (1990)

10.5

| Purkinje cells - peak of neurogenesis

| Finlay and Darlington (1995)

11

| cranial sensory nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

11

| subplate - peak of neurogenesis

| Finlay and Darlington (1995)

11

| reticular nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

11

| medial geniculate nucleus - peak of neurogenesis

| Finlay and Darlington (1995)

11

| globus pallidus - peak of neurogenesis

| Finlay and Darlington (1995)

11.5

| ventral LGN - peak of neurogenesis

| Finlay and Darlington (1995)

12

| dLGN - peak of neurogenesis

| Finlay and Darlington (1995)

12

| cochlear nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

12

| mitral cells - peak of neurogenesis

| Finlay and Darlington (1995)

12

| amygdala - peak of neurogenesis

| Finlay and Darlington (1995)

12

| subplate - end of neurogenesis

| Bayer and Altman (1991)

12.3

| axons in optic stalk

| Dunlop et al. (1997)

12.5

| ventral posterior nucleus (VP) and ventrobasal nucleus (VB) of the thalamus - peak of neurogenesis

| Finlay and Darlington (1995)

12.5

| nucleus of lateral olfactory tract - peak of neurogenesis

| Finlay and Darlington (1995)

12.5

| claustrum - peak of neurogenesis

| Finlay and Darlington (1995)

12.5

| neurogenesis cortical layer VI - peak (VC) of neurogenesis

| Finlay and Darlington (1995)

12.5

| dLGN- end of neurogenesis

| Robinson and Dreher (1990)

12.5

| preoptic nucleus - peak of neurogenesis

| Finlay and Darlington (1995)

13

| medial forebrain bundle appears

| Ashwell et al. (1996)

13

| suprachiasmatic nucleus - peak of neurogenesis

| Finlay and Darlington (1995)

13

| optic axons at chiasm of optic tract

| Dunlop et al. (1997)

13

| superior colliculus - peak of neurogenesis

| Finlay and Darlington (1995)

13

| retinal ganglion cells - peak of neurogenesis

| Finlay and Darlington (1995)

13

| septal nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

13

| entorhinal cortex - peak of neurogenesis

| Finlay and Darlington (1995)

13

| subiculum – peak of neurogenesis

| Finlay and Darlington (1995)

13

| neurogenesis cortical layer V - peak (VC) of neurogenesis

| Finlay and Darlington (1995)

13

| neurogenesis cortical lamina VI - end (VC) of neurogenesis

| Caviness (1982)

13.5

| raphe complex - peak of neurogenesis

| Finlay and Darlington (1995)

13.5

| anterior olfactory nucleus - peak of neurogenesis

| Finlay and Darlington (1995)

13.5

| anteroventral (AV), anterodorsal (AD) and anteromedial (AM) thalamic nuclei - peak of neurogenesis

| Finlay and Darlington (1995)

13.5

| pontine nuclei – peak of neurogenesis

| Finlay and Darlington (1995)

13.5

| parasubiculum – peak of neurogenesis

| Finlay and Darlington (1995)

13.5

| stria terminalis appears

| Ashwell et al. (1996)

13.5

| presubiculum – peak of neurogenesis

| Finlay and Darlington (1995)

14

| fasciculus retroflexus appears

| Finlay and Darlington (1995)

14

| caudoputamen – peak of neurogenesis

| Finlay and Darlington (1995)

14

| superficial SC laminae - end of neurogenesis

| Robinson and Dreher (1990)

14

| fornix appears

| Ashwell et al. (1996)

14

| cones - peak of neurogenesis

| Finlay and Darlington (1995)

14

| neurogenesis cortical layer V - end (VC) of neurogenesis

| Caviness (1982)

14.5

| optic axons reach dLGN and SC

| Robinson and Dreher (1990)

14.5

| anterior commissure appears

| Ashwell et al. (1996)

15

| neurogenesis cortical lamina IV - start (VC) of neurogenesis

| Caviness (1982)

15

| CA 1, CA 2 of hippocampus - peak of neurogenesis

| Finlay and Darlington (1995)

15

| retinal amacrine cells - peak of neurogenesis

| Finlay and Darlington (1995)

15

| hippocampal commissure appears

| Ashwell et al. (1996)

15

| neurogenesis cortical layer II /III - peak (VC) of neurogenesis

| Finlay and Darlington (1995)

15.5

| optic axons invade visual centers

| Dunlop et al. (1997)

16

| nucleus accumbens - peak of neurogenesis

| Finlay and Darlington (1995)

16

| tufted cells - peak of neurogenesis

| Finlay and Darlington (1995)

16

| isles of Calleja - peak of neurogenesis

| Finlay and Darlington (1995)

17

| neurogenesis cortical layer IV - peak (VC) of neurogenesis

| Caviness (1982)

17

| corpus callosum appears

| Ashwell et al. (1996)

17

| neurogenesis cortical layer IV - end (VC) of neurogenesis

| Bayer and Altman (1991)

18.5

| retinal ganglion cell generation - end of neurogenesis

| Robinson and Dreher (1990)

19

| initial differentiation of layer V (S1)

| Finlay and Darlington (1995)

19

| rods - peak of neurogenesis

| Finlay and Darlington (1995)

21

| complete separation of layer V (S1)

| Rice et al. (1985)

22

| onset of barrels (S1)

| Rice et al. (1985)

22

| onset of sublayers in layer V (S1)

| Rice et al. (1985)

22

| onset of trilaminar plate (S1)

| Rice et al. (1985)

24

| onset of barrel field septa (S1)

| Rice et al. (1985)

25.5

| ipsi/contra segregation in LGN and SC

| Robinson and Dreher (1990)

30

| eye opening

| Dunlop et al. (1997)

References

  • {{cite journal | last1=Ashwell | first1=K.W.S. | last2=Waite | first2=P.M.E. | last3=Marotte | first3=L. | title=Ontogeny of the Projection Tracts and Commissural Fibres in the Forebrain of the Tammar Wallaby (Macropus eugenii): Timing in Comparison with Other Mammals | journal=Brain, Behavior and Evolution | publisher=S. Karger AG | volume=47 | issue=1 | year=1996 | issn=0006-8977 | doi=10.1159/000113225 | pages=8–22 | pmid=8834781 }}
  • Clancy, B., Kersh, B., Hyde, J., Darlington, R.B., Anand, K.J.S., Finlay, B.L., 2007. Web-Based Method For Translating Neurodevelopment From Laboratory Species To Humans. Neuroinformatics. 5, pp. 79–94.
  • {{cite journal | last1 = Dunlop | first1 = S.A. | last2 = Tee | first2 = L.B. | last3 = Lund | first3 = R.D. | last4 = Beazley | first4 = L.D. | year = 1997 | title = Development of primary visual projections occurs entirely postnatally in the fat-tailed dunnart, a marsupial mouse, Sminthopsis crassicaudata | journal = J. Comp. Neurol. | volume = 384 | issue = 1 | pages = 26–40 | doi = 10.1002/(sici)1096-9861(19970721)384:1<26::aid-cne2>3.0.co;2-n | pmid = 9214538 | s2cid = 38381685 }}
  • {{cite journal | last1=Finlay | first1=BL | last2=Darlington | first2=RB | title=Linked regularities in the development and evolution of mammalian brains. | journal=Science | volume=268 | issue=5217 | date=1995-06-16 | issn=0036-8075 | pmid=7777856 | pages=1578–84 | doi=10.1126/science.7777856| bibcode=1995Sci...268.1578F }}
  • {{cite journal | last1=Robinson | first1=Stephen R. | last2=Dreher | first2=Bogdan | title=The Visual Pathways of Eutherian Mammals and Marsupials Develop According to a Common Timetable | journal=Brain, Behavior and Evolution | publisher=S. Karger AG | volume=36 | issue=4 | year=1990 | issn=1421-9743 | doi=10.1159/000115306 | pages=177–195 | pmid=2279233 }}

See also

Category:Embryology of nervous system

Category:Developmental neuroscience

Category:Animal nervous system