Mucinous nevus

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| synonym = Nevus mucinosus

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| specialty = Dermatology

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Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired.{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |isbn=978-1-4160-2999-1 }} Mucinous nevus presents as multiple skin-coloured or brown asymptomatic papules or plaques. Mucinous nevus is diagnosed based of histological features. Treatment is not needed.

Signs and symptoms

Mucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid.{{cite journal | last1=Cobos | first1=Gabriela | last2=Braunstein | first2=Inbal | last3=Abuabara | first3=Katrina | last4=Chu | first4=Emily Y. | last5=James | first5=William | title=Mucinous Nevus: Report of a Case and Review of the Literature | journal=JAMA Dermatology | volume=150 | issue=9 | date=2014-09-01 | issn=2168-6068 | doi=10.1001/jamadermatol.2013.9451 | page=1018| pmid=25029469 }}{{cite journal | last1=Tardío | first1=Juan C. | last2=Granados | first2=Rosario | title=The cellular component of the mucinous nevus consists of CD34-positive fibroblasts | journal=Journal of Cutaneous Pathology | publisher=Wiley | volume=37 | issue=9 | date=2010-07-08 | issn=0303-6987 | doi=10.1111/j.1600-0560.2009.01426.x | pages=1019–1020| pmid=19765172 }} It normally starts to develop in early adulthood or from birth.{{cite journal | last1=CHEN | first1=CHIA-WEI | last2=TSAI | first2=TSEN-FANG | last3=CHEN | first3=YU-FU | last4=HUNG | first4=CHIH-MING | title=Familial Mucinous Nevus | journal=Pediatric Dermatology | publisher=Wiley | volume=25 | issue=2 | year=2008 | issn=0736-8046 | doi=10.1111/j.1525-1470.2008.00664.x | pages=288–289| pmid=18429813 }} The main location is the trunk, which includes the back.{{cite journal | last1=Perez-Crespo | first1=M | last2=Lopez-Navarro | first2=N | last3=Betlloch | first3=I | last4=Herrera | first4=E | last5=Niveiro | first5=M | last6=Gallego | first6=E | title=Acquired and familial mucinous nevus | journal=International Journal of Dermatology | publisher=Wiley | volume=50 | issue=10 | date=2011-09-25 | issn=0011-9059 | doi=10.1111/j.1365-4632.2010.04520.x | pages=1283–1285| pmid=21950298 }}

Causes

There has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.

Diagnosis

Histologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus.{{cite journal | last1=Lee | first1=Min Young | last2=Byun | first2=Ji Yeon | last3=Choi | first3=Hae Young | last4=Choi | first4=You Won | title=Mucinous Nevus | journal=Annals of Dermatology | publisher=Korean Dermatological Association and The Korean Society for Investigative Dermatology | volume=30 | issue=4 | year=2018 | pages=465–467 | issn=1013-9087 | doi=10.5021/ad.2018.30.4.465 | pmid=30065589 | pmc=6029955 }} Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.{{cite journal | last1=Lim | first1=J-H. | last2=Cho | first2=S-H. | last3=Kim | first3=H-O. | last4=Kim | first4=C-W. | last5=Park | first5=Y-M. | title=Mucinous naevus with atypical features | journal=British Journal of Dermatology | publisher=Oxford University Press (OUP) | volume=148 | issue=5 | year=2003 | issn=0007-0963 | doi=10.1046/j.1365-2133.2003.05334.x | pages=1064–1066| pmid=12786849 }}{{cite journal | last1=BRAKMAN | first1=M. | last2=STARINK | first2=TH.M. | last3=TAFELKRUYER | first3=J. | last4=BOS | first4=J.D. | title=Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus') | journal=British Journal of Dermatology | publisher=Oxford University Press (OUP) | volume=131 | issue=3 | year=1994 | issn=0007-0963 | doi=10.1111/j.1365-2133.1994.tb08526.x | pages=368–370}}

Treatment

Mucinous nevi are benign and don't need to be treated other than for aesthetic reasons. Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.{{cite journal | last1=Chi | first1=Ching-Chi | last2=Wang | first2=Shu-Hui | last3=Lin | first3=Paul Y. | title=Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review | journal=Journal of Cutaneous Pathology | publisher=Wiley | volume=36 | issue=7 | year=2009 | issn=0303-6987 | doi=10.1111/j.1600-0560.2008.01123.x | pages=808–811| pmid=19519615 }}

References

External links

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| ICD11 = {{ICD11|LC20}}

| ICD10 = {{ICD10|L98.5}}

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Category:Epidermal nevi, neoplasms, and cysts