Mycobacterium gordonae

{{Short description|Species of bacterium}}

{{Speciesbox

| taxon = Mycobacterium gordonae

| authority = Bojalil et al. 1962, ATCC 14470

}}

Mycobacterium gordonae is a species of Mycobacterium named for Ruth E. Gordon.{{EMedicine|article|223038|Mycobacterium gordonae}} It is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

Description

File:Slant tubes of Löwenstein-Jensen medium with control, M tuberculosis, M avium and M gordonae.jpg. From left to right:
- Negative control
- M. tuberculosis: Dry-appearing colonies
- Mycobacterium avium complex: Wet-appearing colonies
- M. gordonae: Yellowish colonies]]

Gram-positive, nonmotile and moderate to long acid-fast rods.

  • Commonly found in tap water and soil. Casual resident in human sputum and gastric lavage specimens.

Colony characteristics

Physiology

  • Growth on Löwenstein-Jensen medium and Middlebrook 7H10 agar within 7 or more days at 37 °C (optimal 25 °C).
  • Does not grow in the presence of ethambutol (1 mg/L), isoniazid (10 mg/L) and sodium chloride (5%).
  • Some strains can grow using carbon monoxide as a carbon and energy source.{{cite journal | vauthors = King GM | title = Uptake of carbon monoxide and hydrogen at environmentally relevant concentrations by mycobacteria | journal = Applied and Environmental Microbiology | volume = 69 | issue = 12 | pages = 7266–72 | date = December 2003 | pmid = 14660375 | pmc = 310020 | doi = 10.1128/aem.69.12.7266-7272.2003 }}

Differential characteristics

  • A commercial hybridisation assay (AccuProbe) to identify M. gordonae exists.{{cite journal | vauthors = Reisner BS, Gatson AM, Woods GL | title = Use of Gen-Probe AccuProbes to identify Mycobacterium avium complex, Mycobacterium tuberculosis complex, Mycobacterium kansasii, and Mycobacterium gordonae directly from BACTEC TB broth cultures | journal = Journal of Clinical Microbiology | volume = 32 | issue = 12 | pages = 2995–8 | date = December 1994 | doi = 10.1128/JCM.32.12.2995-2998.1994 | pmid = 7883888 | pmc = 264213 }}
  • Intraspecies variability in 16S rDNA sequences

Pathogenesis

  • Rarely if ever implicated in disease processes even if patients are immunocompromised. Widely distributed in environment and usually a contaminant in laboratory specimens.{{Cite web|url=https://www.nationaljewish.org/conditions/ntm-nontuberculous-mycobacteria/ntm-nontuberculous-mycobacteria-overview/types|title=NTM: Types|last=Kasperbauer|first=Shannon|date=July 1, 2017|website=National Jewish Health}}
  • Biosafety level 2

Type strain

Strain ATCC 14470 = CCUG 21801 = CCUG 21811 = CIP 104529 = DSM 44160 = JCM 6382 = NCTC 10267.

References

{{Reflist}}

Further reading

  • {{cite journal | vauthors = Bojalil LF, Cerbon J, Trujillo A | title = Adansonian classification of mycobacteria | journal = Journal of General Microbiology | volume = 28 | issue = 2 | pages = 333–46 | date = June 1962 | pmid = 13870716 | doi = 10.1099/00221287-28-2-333 | doi-access = free }}