Mycobacterium haemophilum

{{Speciesbox

| taxon = Mycobacterium haemophilum

| authority = Sompolinsky et al. 1978, ATCC 29548

}}{{More citations needed|date=May 2015}}

Mycobacterium haemophilum is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.

Description

Short, occasionally curved, gram-positive, nonmotile and strongly acid-fast rods.

Colony characteristics

Physiology

Media have to be supplemented with 0.4% haemoglobin or 60 μM hemin (factor X) or 15 mg/ml ferric ammonium citrate respectively, but not with FeCl₃ or catalase.
Slow growth on Löwenstein–Jensen medium or Middlebrook 7H10 agar at 32 °C within 2 to 4 weeks.
Growth slower at 25 °C and 35 °C and absent at 37 °C.
Strictly intracellular growth in tissue cultures of fibroblasts.

Differential characteristics

Unique among mycobacteria in its requirement for hemin or ferric ammonium citrate for growth.

Distribution.

Infects patients with suppressed immune systems.{{EMedicine|article|223133|Mycobacterium Haemophilum}}
Clinical presentation: multiple skin nodules occurring in clusters or without definitive pattern, commonly involving the extremities. Abscesses, draining fistulas and osteomyelitis may be associated with the nodules. Paediatric patients with localised cervical lymphadenopathy.
Biosafety level 2

First isolated in Israel from a subcutaneous granuloma from a patient with Hodgkin's disease. An environmental reservoir is presumed.

Strain ATCC 29548 = CCUG 47452 = CIP 105049 = DSM 44634 = NCTC 11185.

{{cite journal |doi=10.1099/00207713-28-1-67 |title=Mycobacterium haemophilum sp. nov., a New Pathogen of Humans |journal=International Journal of Systematic Bacteriology |volume=28 |issue=1 |pages=67–75 |year=1978 |last1=Sompolinsky |first1=D. |last2=Lagziel |first2=A. |last3=Naveh |first3=D. |last4=Yankilevitz |first4=T. |doi-access=free }}

[http://bacdive.dsmz.de/index.php?search=8513&submit=Search Type strain of Mycobacterium haemophilum at BacDive - the Bacterial Diversity Metadatabase]