N-Ethylbuphedrone
{{Short description|Stimulant of the cathinone class}}
{{DISPLAYTITLE:N-Ethylbuphedrone}}
{{Drugbox
| drug_name = N-Ethylbuphedrone
| IUPAC_name = 2-(Ethylamino)-1-phenylbutan-1-one
| image = N-Ethylbuphedrone.svg
| image_class = skin-invert-image
| width = 220
| tradename =
| routes_of_administration =
| legal_DE = Anlage I
| legal_UK = Class B
| legal_status =
| CAS_number = 1354631-28-9
| ATC_suffix =
| PubChem = 20326296
| ChemSpiderID = 15397161
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = VUF6VC063Q
| C=12 | H=17 | N=1 | O=1
| smiles = CCNC(CC)C(=O)c1ccccc1
| StdInChI = 1S/C12H17NO/c1-3-11(13-4-2)12(14)10-8-6-5-7-9-10/h5-9,11,13H,3-4H2,1-2H3
| StdInChIKey = HEPVRDHGUWFXJS-UHFFFAOYSA-N
}}
N-Ethylbuphedrone (also known as NEB) is a stimulant of the cathinone class that has been sold as a designer drug.{{cite journal | vauthors = Lanza M, Acton WJ, Jürschik S, Sulzer P, Breiev K, Jordan A, Hartungen E, Hanel G, Märk L, Mayhew CA, Märk TD | display-authors = 6 | title = Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS) | journal = Journal of Mass Spectrometry | volume = 48 | issue = 9 | pages = 1015–1018 | date = September 2013 | pmid = 24078242 | doi = 10.1002/jms.3253 | bibcode = 2013JMSp...48.1015L }}{{cite journal | vauthors = Acton WJ, Lanza M, Agarwal B, Jürschik S, Sulzer P, Breiev K, Jordan A, Hartungen E, Hanel G, Märk L, Mayhew CA, Märk TD | display-authors = 6 | title = Headspace analysis of new psychoactive substances using a Selective Reagent Ionisation-Time of Flight-Mass Spectrometer | journal = International Journal of Mass Spectrometry | volume = 360 | pages = 28–38 | date = March 2014 | pmid = 25844048 | doi = 10.1016/j.ijms.2013.12.009 | pmc = 4375562 | bibcode = 2014IJMSp.360...28A }}{{cite journal | vauthors = Uralets V, Rana S, Morgan S, Ross W | title = Testing for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine | journal = Journal of Analytical Toxicology | volume = 38 | issue = 5 | pages = 233–241 | date = June 2014 | pmid = 24668489 | doi = 10.1093/jat/bku021 | doi-access = free }}{{cite journal | vauthors = Pieprzyca E, Skowronek R, Czekaj P | title = Toxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and other Drugs of Abuse | journal = Journal of Analytical Toxicology | date = November 2021 | volume = 46 | issue = 9 | pages = 1008–1015 | pmid = 34849994 | doi = 10.1093/jat/bkab119 }} It is the β-ketone analogue of N,alpha-diethylphenylethylamine.
Legal status
As of October 2015 NEB is a controlled substance in China.{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=zh | access-date=1 October 2015 | archive-url=https://web.archive.org/web/20151001222554/http://www.sfda.gov.cn/WS01/CL0056/130753.html | archive-date=1 October 2015 | url-status=dead }}
In the United States NEB is considered a schedule 1 controlled substance as a positional isomer of 4-Methylethcathinone (4-MEC) {{Cite report |url=https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf |title=Lists of: Scheduling Actions; Controlled Substances; Regulated Chemicals |last=Diversion Control Division |date=February 2023 |publisher=U.S. Department of Justice, Drug Enforcement Administration |archive-url=https://web.archive.org/web/20230306171250/https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf |archive-date=2023-03-06 |url-status=live}}
See also
References
{{Reflist}}
{{Stimulants}}
{{Monoamine releasing agents}}
{{Phenethylamines}}
{{DEFAULTSORT:Ethylbuphedrone, N-}}
Category:Norepinephrine-dopamine releasing agents
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