N-substituted formamide deformylase

{{DISPLAYTITLE:N-substituted formamide deformylase}}

{{infobox enzyme

| Name = N-substituted formamide deformylase

| EC_number = 3.5.1.91

| CAS_number =

| GO_code =

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In enzymology, a N-substituted formamide deformylase ({{EC number|3.5.1.91}}) is an enzyme that catalyzes the chemical reaction

:N-benzylformamide + H₂O $\backslash rightleftharpoons$ formate + benzylamine

Thus, the two substrates of this enzyme are N-benzylformamide and H₂O, whereas its two products are formate and benzylamine.{{cite journal | vauthors = Fukatsu H, Hashimoto Y, Goda M, Higashibata H, Kobayashi M | title = Amine-synthesizing enzyme N-substituted formamide deformylase: screening, purification, characterization, and gene cloning | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 38 | pages = 13726–31 | date = September 2004 | pmid = 15358859 | pmc = 518824 | doi = 10.1073/pnas.0405082101 | bibcode = 2004PNAS..10113726F | doi-access = free }}

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzylformamide amidohydrolase and is also called NfdA. The enzyme is produced by Arthrobacter pascens bacteria.{{cite book| chapter-url = https://books.google.com/books?id=hN38HsVK5HgC&q=benzylformamide&pg=PA376|chapter = 3.5.1.91 N-substituted formamide deformylase|pages = 376–378|title = Class 3 Hydrolases: EC 3.4.22-3.13|series = Springer Handbook of Enzymes|editor1-first = D.|editor1-last = Schomburg|editor2-first = I.|editor2-last = Schomburg|editor3-last = Chang|editor3-first = A. | name-list-style = vanc |edition = 2nd|publisher = Springer Science & Business Media|year = 2009|isbn = 9783540857051}}