NPDC1

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Neural proliferation differentiation and control protein 1 is a protein that in humans is encoded by the NPDC1 gene.{{cite journal | vauthors = Qu X, Zhang C, Zhai Y, Xing G, Wei H, Yu Y, Wu S, He F | title = Characterization and tissue expression of a novel human gene npdc1 | journal = Gene | volume = 264 | issue = 1 | pages = 37–44 | date = March 2001 | pmid = 11245976 | doi = 10.1016/S0378-1119(01)00324-9 }}{{cite web | title = Entrez Gene: NPDC1 neural proliferation, differentiation and control, 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56654}}

Interactions

NPDC1 has been shown to interact with E2F1.{{cite journal | vauthors = Sansal I, Dupont E, Toru D, Evrard C, Rouget P | title = NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity | journal = Oncogene | volume = 19 | issue = 43 | pages = 5000–9 | date = October 2000 | pmid = 11042687 | doi = 10.1038/sj.onc.1203843 | doi-access = free }}

References

{{reflist}}

Further reading

{{refbegin | 2}}

  • {{cite journal | vauthors = Dupont E, Sansal I, Toru D, Evrard C, Rouget P | title = [Identification of NPDC-1, gene involved in the control of proliferation and differentiation of neural and glial precursors] | journal = C. R. Séances Soc. Biol. Fil. | volume = 191 | issue = 1 | pages = 95–104 | year = 1997 | pmid = 9181131 }}
  • {{cite journal | vauthors = Galiana E, Vernier P, Dupont E, Evrard C, Rouget P | title = Identification of a neural-specific cDNA, NPDC-1, able to down-regulate cell proliferation and to suppress transformation | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 5 | pages = 1560–4 | year = 1995 | pmid = 7878019 | pmc = 42559 | doi = 10.1073/pnas.92.5.1560 | bibcode = 1995PNAS...92.1560G | doi-access = free }}
  • {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
  • {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
  • {{cite journal | vauthors = Iwasaki K, Toyonaga R | title = The Rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission | journal = EMBO J. | volume = 19 | issue = 17 | pages = 4806–16 | year = 2000 | pmid = 10970871 | pmc = 302062 | doi = 10.1093/emboj/19.17.4806 }}
  • {{cite journal | vauthors = Sansal I, Dupont E, Toru D, Evrard C, Rouget P | title = NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity | journal = Oncogene | volume = 19 | issue = 43 | pages = 5000–9 | year = 2000 | pmid = 11042687 | doi = 10.1038/sj.onc.1203843 | doi-access = free }}
  • {{cite journal | vauthors = Spencer ML, Theodosiou M, Noonan DJ | title = NPDC-1, a novel regulator of neuronal proliferation, is degraded by the ubiquitin/proteasome system through a PEST degradation motif | journal = J. Biol. Chem. | volume = 279 | issue = 35 | pages = 37069–78 | year = 2004 | pmid = 15229225 | doi = 10.1074/jbc.M402507200 | doi-access = free }}
  • {{cite journal | vauthors = Evrard C, Caron S, Rouget P | title = Functional analysis of the NPDC-1 gene | journal = Gene | volume = 343 | issue = 1 | pages = 153–63 | year = 2004 | pmid = 15563841 | doi = 10.1016/j.gene.2004.08.020 }}
  • {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}

{{refend}}

{{gene-9-stub}}