Nader Pourmand

{{Short description|Professor of Biomolecular Engineering}}

Nader Pourmand is a Professor of Biomolecular Engineering leading the Biosensors and Bioelectrical Technology Group at the Baskin School of Engineering at the University of California Santa Cruz, Baskin School of Engineering.{{Cite web|title=Nader Pourmand {{!}} Jack Baskin School of Engineering|url=https://www.soe.ucsc.edu/people/pourmand|access-date=2021-06-21|website=www.soe.ucsc.edu}}

He has been published in Cancer Research,{{Cite journal|date=2007-07-01|title=Cancer Research: 67 (13)|url=http://cancerres.aacrjournals.org/content/vol67/issue13/|journal=Cancer Research|language=en|volume=67|issue=13|issn=0008-5472}} PLoS ONE,{{Cite web|title=PLOS ONE: Infectious diseases|url=https://journals.plos.org/plosone/browse/Infectious_Diseases|access-date=2020-06-13|website=journals.plos.org}} ACS, and the Proceedings of the National Academy of Sciences.{{Cite journal|last1=Pourmand|first1=Nader|last2=Karhanek|first2=Miloslav|last3=Persson|first3=Henrik H. J.|last4=Webb|first4=Chris D.|last5=Lee|first5=Thomas H.|last6=Zahradníková|first6=Alexandra|last7=Davis|first7=Ronald W.|date=2006-04-25|title=Direct electrical detection of DNA synthesis|journal=Proceedings of the National Academy of Sciences|language=en|volume=103|issue=17|pages=6466–6470|doi=10.1073/pnas.0601184103|issn=0027-8424|pmc=1458907|pmid=16614066|bibcode=2006PNAS..103.6466P|doi-access=free}}

Pourmand received his PhD at the Karolinska Institute, Stockholm, Sweden.{{Cite web|title=Colloquium Speaker: Nader Pourmand; Professor, Department of Biomolecular Engineering, University of California, Santa Cruz|url=https://www.bioeng.ucr.edu/event-list/2019/02/06/colloquium-speaker-nader-pourmand-professor-department-biomolecular|access-date=2021-06-21|website=Bioengineering|language=en}} While he was at Stanford, his lab developed the science underlying Ion Torrent, a benchtop next-gen sequencing system (acquired by Life Technologies, then by Thermo Fisher).{{Cite web|title=Nader Pourmand and Ion Torrent {{!}} Genomics Institute|url=https://ucscgenomics.soe.ucsc.edu/nader-pourmand-and-ion-torrent/|access-date=2021-06-21|language=en-US}} He has been a cofounder of start-ups Pinpoint Science inc.,{{Cite web|last=Stephens|first=Tim|title=COVID Catalyst Fund supports work on rapid serology test at UC Santa Cruz|url=https://news.ucsc.edu/2020/05/nanosensor.html|access-date=2021-06-21|website=UC Santa Cruz News|language=en}} BioStinger Inc. (now part of Yokogawa, Japan),{{Cite web|title=Yokogawa Electric's Acquisition of BioStinger Technology {{!}} Genomics Institute|url=https://ucscgenomics.soe.ucsc.edu/yokogawa-electrics-acquisition-of-biostinger-technology/|access-date=2021-06-21|language=en-US}} MagArray Inc.,{{Cite web|last1=Stephens|first1=Tim|last2=Writer 459-2495|first2=Staff|title=Magnetic nanotags allow sensitive detection of cancer biomarkers|url=https://news.ucsc.edu/2008/12/2587.html|access-date=2021-06-21|website=UC Santa Cruz News|language=en}} and contributed to others including Nvigen,{{Cite journal|last1=Chaves|first1=Gepoliano|last2=Stanley|first2=John|last3=Pourmand|first3=Nader|date=2019-08-23|title=Mutant Huntingtin Affects Diabetes and Alzheimer's Markers in Human and Cell Models of Huntington's Disease|journal=Cells|volume=8|issue=9|page=962|doi=10.3390/cells8090962|issn=2073-4409|pmc=6769852|pmid=31450785|doi-access=free}} Ion Torrent, Bioprobix, and Pathogenix.{{cite news|title=Point-of-Care Molecular Detection for Pathogen Testing|url=https://nccavs-usergroups.avs.org/wp-content/uploads/2020/09/Purmand-1.pdf|accessdate=21 June 2021}}

He has developed technology based on functionalized nanopipettes, which can be used to study genomics and proteomics of individual living cells at nanoscale.{{Cite journal|last1=Actis|first1=Paolo|last2=Mak|first2=Andy C.|last3=Pourmand|first3=Nader|date=2010|title=Functionalized nanopipettes: toward label-free, single cell biosensors|journal=Bioanalytical Reviews|volume=1|issue=2|pages=177–185|doi=10.1007/s12566-010-0013-y|issn=1867-2086|pmc=2918800|pmid=20730113}}{{Cite journal|last1=Bulbul|first1=Gonca|last2=Chaves|first2=Gepoliano|last3=Olivier|first3=Joseph|last4=Ozel|first4=Rifat Emrah|last5=Pourmand|first5=Nader|date=2018-06-06|title=Nanopipettes as Monitoring Probes for the Single Living Cell: State of the Art and Future Directions in Molecular Biology|journal=Cells|volume=7|issue=6|page=55|doi=10.3390/cells7060055|issn=2073-4409|pmc=6024992|pmid=29882813|doi-access=free}} This nanopipette technology was described in Nature Nanotechnology as a major advance in Single cell genomics and was recognized by the NIH for the development of this technology for interrogating single living cells.{{Cite journal|last=Brown|first=Sarah|date=2014-01-06|title=Interrogating single cells|url=https://www.nature.com/articles/nnano.2013.307|journal=Nature Nanotechnology|language=en|pages=1|doi=10.1038/nnano.2013.307|issn=1748-3395|doi-access=free}}{{Cite journal|last1=Laborde|first1=C.|last2=Pittino|first2=F.|last3=Verhoeven|first3=H. A.|last4=Lemay|first4=S. G.|last5=Selmi|first5=L.|last6=Jongsma|first6=M. A.|last7=Widdershoven|first7=F. P.|title=Real-time imaging of microparticles and living cells with CMOS nanocapacitor arrays|url=https://www.nature.com/articles/nnano.2015.163|journal=Nature Nanotechnology|year=2015|language=en|volume=10|issue=9|pages=791–795|doi=10.1038/nnano.2015.163|pmid=26237346|bibcode=2015NatNa..10..791L|hdl=11380/1163314 |issn=1748-3395|hdl-access=free}} This same nanopipette technology is the basis for Pinpoint Science Inc's handheld diagnostic platform for detecting microbial pathogens.