Nepinalone

{{Short description|Chemical compound}}

{{Drugbox

| Watchedfields = changed

| verifiedrevid = 444509259

| IUPAC_name = 1-methyl-1-(2-piperidin-1-ylethyl)-3,4-dihydronaphthalen-2(1H)-one

| image = Nepinalone.png

| width = 120px

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| CAS_number = 22443-11-4

| ATC_prefix = R05

| ATC_suffix = DB26

| PubChem = 3047788

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 2310106

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = L9806LPR7G

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D07396

| C=18 | H=25 | N=1 | O=1

| smiles = O=C2C(c1ccccc1CC2)(CCN3CCCCC3)C

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C18H25NO/c1-18(11-14-19-12-5-2-6-13-19)16-8-4-3-7-15(16)9-10-17(18)20/h3-4,7-8H,2,5-6,9-14H2,1H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = RVXGRCNWGOHSDE-UHFFFAOYSA-N

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Nepinalone is a cough suppressant. Its brand names include Placatus, Tussolvina, and Nepitus.

The effect is evident after 20–30 minutes after administration and persists for at least 4 hours. It acts primarily at the level of the CNS, but also shows a slight activity in inhibiting the bronchospasm. In such use, it is less effective than codeine and more effective than dextromethorphan in inhibiting the tussive stimulus.

[https://www.drugs.com/international/nepinalone.html] {{Webarchive|url=https://web.archive.org/web/20190817135734/https://www.drugs.com/international/nepinalone.html |date=2019-08-17 }}