Nexafed

Nexafed is a formulation of pseudoephedrine developed by Acura Pharmaceuticals used to deter the use of the pseudoephedrine contained in the product for illicit methamphetamine synthesis.{{cite web|url=http://www.cbsnews.com/news/in-fight-against-crystal-meth-a-focus-on-chemistry/|title=In fight against crystal meth, a focus on chemistry|work=cbsnews.com|date=2 August 2013 |accessdate=18 July 2016}} Nexafed uses a polymer matrix that forms a thick gel when hydrated, preventing the extraction of pseudoephedrine.{{Cite web|last=Ricker|first=Nok-Noi|date=2016-07-02|title=Pharmacies in northern Maine halt sales of certain decongestants to thwart meth labs|url=http://bangordailynews.com/2016/07/02/news/pharmacies-in-northern-maine-halt-sales-of-certain-decongestants-to-thwart-meth-labs/|access-date=2021-11-07|website=Bangor Daily News|language=en-US}} Nexafed is the only meth-resistant formulation of pseudoephedrine that shows therapeutic equivalence to Sudafed.{{Cite journal|last1=Brzeczko|first1=Albert W.|last2=Leech|first2=Ronald|last3=Stark|first3=Jeffrey G.|title=The advent of a new pseudoephedrine product to combat methamphetamine abuse|journal=The American Journal of Drug and Alcohol Abuse|year=2013 |language=en|volume=39|issue=5|pages=284–290|doi=10.3109/00952990.2013.821476|issn=0095-2990|pmc=3793278|pmid=23968171}}

It is sold at various pharmacies in the US, including Fruth Pharmacy{{cite web|url=http://www.drugstorenews.com/article/fruth-pharmacy-recognized-fighting-meth-production|title=Fruth Pharmacy recognized for fighting meth production|work=drugstorenews.com|accessdate=18 July 2016}}{{cite web|url=http://www.wsaz.com/home/headlines/Fruth-Pharmacy-Stops-Selling-Certain--221325031.html|title=Fruth Pharmacy to Stop Selling Certain Medications to Fight Meth Abuse|author=Anna Baxter, The Associated Press|work=wsaz.com|accessdate=18 July 2016}} and Kroger, particularly in communities where illicit methamphetamine production is an issue.{{Citation needed|date=November 2021}}