Nicholas Tatonetti

Tatonetti is originally from Cleveland, Ohio.{{cite web| url = https://science.osti.gov/-/media/wdts/scgf/pdf/2010Profiles/TatonettiNicholas_Profile.pdf| title = U.S. Department of Energy profile| website = U.S. Department of Energy | date = 2016-09-10| access-date = 2024-01-14}} In 2008, Tatonetti double-majored with bachelors degrees in Computational Mathematical Sciences as well as Molecular Biosciences and Biotechnology at the Tempe campus of Arizona State University.{{Cite web |title=Faces of AMIA: Nicholas Tatonetti |url=https://amia.org/about-amia/faces-amia/faces-amia-nicholas-tatonetti |access-date=2022-10-05 |website=AMIA - American Medical Informatics Association |language=en}} In his senior year at ASU, he was elected to Phi Beta Kappa, and graduated Summa Cum Laude. {{cite web| url = https://www.tatonetti.com/cv.html| title = Curriculum Vitae| author = Nicholas Tatonetti| website = Tatonetti Lab| publisher =| access-date = 2023-12-06}}

He went on to Stanford University as a graduate researcher in biomedical informatics, where he was advised under Russ Altman.{{Cite web |last=Hackett |first=Stephen M. |date=2011-05-25 |title=Doctoral candidate uses MacBook Pro to track drug interactions |url=https://www.macgasm.net/news/apple-inc-news/doctoral-candidate-macbook-pro-track-drug-interactions/ |access-date=2022-10-05 |website=Macgasm |language=en-US}} Fellow graduate researchers during his doctoral studies include Joel Dudley and Noah Zimmerman. As a co-curricular, Tatonetti and Zimmerman hosted The Nick and Noah Show on KZSU radio from 2010 to 2012. {{cite web

| url = https://zookeeper.stanford.edu/?subaction=viewDJ&seq=selUser&viewuser=849| title = Nick & Noah's Recent airplay| author = | website = Stanford Zookeeper| publisher = [Publisher's Name, if applicable]| access-date = 2023-12-06}}

Over the span of the show, they interviewed notable faculty at Stanford, including Michael P. Snyder, David Spiegel, and Nobel Laureate Andrew Fire. {{cite web| url = http://nickandnoah.com/| title = Nick and Noah: The Radio Show| website = Wayback Machine| date = 2012-06-28| archive-url = https://web.archive.org/web/20130620224153/http://nickandnoah.com/| access-date =2023-12-06| archive-date = 20 June 2013}}

During his PhD, Tatonetti developed a classifier to detect side effects of drugs based on data available by FAERS.{{cite web |url=https://tedmed.com/talks/show?id=529433 |title=Russ Altman's TEDMED Talk |publisher=TEDMED |access-date=2023-12-03}} His dissertation, titled Data-driven detection, prediction, and validation of drug-drug interactions, focused on the development of novel statistical and computational methods for observational data mining.{{Cite web |title=Nicholas Tatonetti – OHDSI |url=https://ohdsi.org/who-we-are/collaborators/nicholas-tatonetti/ |access-date=2022-10-05 |language=en-US}} His dissertation committee included Altman, Atul J. Butte, Trevor Hastie, and Phil Tsao. He received his MS and PhD in Biomedical Informatics from Stanford University School of Medicine in 2012.

In 2012, Tatonetti started his teaching career as the Herbert Irving Assistant Professor of Biomedical Informatics at Columbia University. He moved up to Associate Professor in 2019. {{cite web| url = https://www.dbmi.columbia.edu/non-traditional-thinking-guides-nick-tatonetti-ph-d-to-important-advancements-in-health-healthcare/| title = Non-Traditional Thinking Guides Nicholas Tatonetti, Ph.D., To Important Advancements In Health, Healthcare| website = Columbia DBMI| date = 9 July 2019| access-date = 2023-12-06}} In 2017, he became both the Director of Clinical Informatics at the Institute for Genomic Medicine and the Co-Director of Bioinformatics at the Department of Biomedical Informatics at Columbia. {{cite web| url = https://systemsbiology.columbia.edu/news/tatonetti-named-director-of-clinical-informatics-at-institute-for-genomic-medicine| title = Tatonetti Named Director of Clinical Informatics at Institute for Genomic Medicine| website = Columbia University Department of Systems Biology| date = 2018-01-08| access-date = 2023-12-06}} During his tenure at Columbia, notable collaborators included Brent Stockwell, Suzanne Bakken, and David Goldstein.

In 2014, Tattonetti published a groundbreaking study revealing a statistical correlation between birth month and the likelihood of different disease diagnoses later in life. This intriguing finding captured global attention, leading to the study becoming the most downloaded paper in the history of the Journal of the American Medical Informatics Association (JAMIA). Notably, it also marked Tattonetti's research's sole mention in Vogue magazine to date.{{cite web| url = https://www.linkedin.com/pulse/tlab-moves-los-angeles-nicholas-tatonetti/| title =TLab moves to Los Angeles | website = linkedin.com/ | publisher = LinkedIn| access-date = 2023-12-17}}

From 2016 to 2018, Tatonetti collaborated with Pulitzer Prize-winning journalist Sam Roe of the Chicago Tribune. During their two-year collaboration, Tatonetti was introduced to the physician Raymond Woosley, who provided a list of medications known to cause QT prolongation of the heart. {{cite web| url = https://www.cuimc.columbia.edu/news/dangerous-drug-interactions-uncovered-data-science| title = Dangerous Drug Interactions Uncovered with Data Science| website = Columbia University Irving Medical Center| date = 2016-10-10| access-date = 2023-12-06}}

From that initial data, they discovered that ceftriaxone and lansoprazole prescribed together induce heart arrhythmias in patients. {{cite web |url=https://systemsbiology.columbia.edu/news/nicholas-tatonetti-phd-always-thinking-outside-the-box |title=Nicholas Tatonetti, PhD: Always Thinking Outside the Box |publisher=Columbia University Department of Systems Biology |access-date=2023-12-03}}{{cite web |url=https://radiohealthjournal.org/big-data-in-medicine-2/ |title=Big Data in Medicine |date=June 5, 2016 |website=Radio Health Journal |access-date=2023-12-04}}

In 2018, Tatonetti and Zimmerman along with illustrator and educator Cybil Sanzetenea co-authored the board book Toshi Builds Consensus: A blockchain primer for kids (and grown-ups).{{cite web| url = https://medium.com/@tatonetti/toshi-finds-an-illustrator-18fffe9734fc| title = Toshi Finds an Illustrator| author = Nicholas Tatonetti| website = Medium| date = 2018-11-14| access-date = 2023-12-06}} Published in 2020, the purpose was create a book to expose K-12 students to STEM literacy early in the likelihood this will encourage them to develop careers in STEM as adults. {{cite web| url = https://medium.com/@tatonetti/science-early-science-often-6ea72e935afa| title = Science Early, Science Often| author = Nicholas Tatonetti| website = Medium| date = 2018-10-31| access-date = 2023-12-06}}{{cite web| url = https://medium.com/@tatonetti/two-professors-wrote-the-worlds-first-blockchain-board-book-for-kids-9de9eeac7b24| title = Two Professors Wrote the World's First Blockchain Board Book for Kids| author = Nicholas Tatonetti| website = Medium| date = 2018-11-14| access-date = 2023-12-06}}

In 2020, Tatonetti hosted The C19 Weekly videocast on the American Medical Informatics Association website, where he discussed the recent data science and bioinformatics-oriented COVID-19 research papers.{{cite web| url = https://amia.org/news-publications/amia-covid-19-resource-center/c19-weekly-vidcast| title = C19 Weekly Vidcast | website = amia.org| publisher = American Medical Informatics Association| access-date = 2023-12-06}}

In addition to his teaching responsibilities at Columbia, in 2013, he became the Director of Clinical Informatics at Herbert Irving Comprehensive Cancer Center. In 2022, he was promoted to Chief Officer for Cancer Data Science.

In 2023, Tatonetti joined Cedars-Sinai Medical Center as the vice chair of Computational Biomedicine and associate director for Computational Oncology. He is a key contributor to the Molecular Twin project, which involves collecting genetic data from cancer patients to create virtual models to better understand the unique attributes of their cancer. This would allow healthcare practitioners at Cedars-Sinai to identify personalized treatment strategies for each patient (i.e. pharmacogenomics). {{cite web| url = https://www.cedars-sinai.org/newsroom/molecular-twin-initiative-will-help-advance-precision-cancer-treatment/| title = 'Molecular Twin' Initiative To Help Advance Cancer Treatment| website = Cedars-Sinai Newsroom| date = 2016-09-10| access-date = 2023-12-06}}

In January 2025, Tatonetti was named the new co-editor-in-chief of BioData Mining with his colleague Jason H. Moore.{{Cite web|title=BioData Mining|url=https://biodatamining.biomedcentral.com/|website=BioMed Central|publisher=Springer Nature|access-date=22 April 2025}}

Tatonetti has described himself as pansexual and gender non-conforming.{{Cite web |title=Nicholas Tatonetti |url=https://500queerscientists.com/nicholas-tatonetti/ |access-date=2022-10-05 |website=500 Queer Scientists |language=en-US}}

• {{Cite Q|Q102058933}}
• {{Cite Q|Q33745283|doi-access=free}}
• {{Cite Q|Q24599300}}

{{Reflist}}

{{authority control}}

{{DEFAULTSORT:Tatonetti, Nicholas}}

Category:Living people

Category:Arizona State University alumni

Category:Stanford University alumni

Category:Columbia University faculty

Category:American scientists

Category:Year of birth missing (living people)

{{catimprove|date=October 2022}}