Nicotine lozenge
{{Short description|Nicotine product for tobacco cessation}}
{{More medical citations needed|date=October 2018}}
A nicotine lozenge is a modified-release dosage tablet (usually flavored) that contains a dose of nicotine polacrilex, which dissolves slowly in the mouth to release nicotine over the course of 20 to 30 minutes. Nicotine lozenges are intended to help individuals quit smoking and are generally an over-the-counter medication. Nicotine lozenges are commonly found in 2 mg and 4 mg strengths, although other strengths may be found. The nicotine is absorbed through the lining of the mouth and enters the blood vessels. It is used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation.{{Cite web|url=https://www.nicorette.com/faq.html|title=Frequently Asked Questions {{!}} Nicorette|website=www.nicorette.com|language=en-US|access-date=2019-10-31}}
Side effects
- Nausea
- Mouth irritation
- Sore throat
- Heartburn
- Hiccups
- Cravings for cigarettes
- Restlessness
- Difficulty concentrating{{Cite journal|last1=Pack|first1=Quinn R.|last2=Jorenby|first2=Douglas E.|last3=Fiore|first3=Michael C.|last4=Jackson|first4=Thomas|last5=Weston|first5=Patricia|last6=Piper|first6=Megan E.|last7=Baker|first7=Timothy B.|date=August 2008|title=A Comparison of the Nicotine Lozenge and Nicotine Gum An Effectiveness Randomized Controlled Trial|journal=WMJ |volume=107|issue=5|pages=237–243|issn=1098-1861|pmc=3174063|pmid=18777992}}{{Cite web|url=https://www.nicorette.com/about-nicorette/nicorette-side-effects.html|title=Safety & Side Effects {{!}} Nicorette|website=www.nicorette.com|language=en-US|access-date=2019-11-14}}
Drug interactions
There are few interactions between nicotine and prescription medications (e.g., adenosine, cimetidine, varenicline), but the act of quitting smoking can impact the effect of other medications.{{Cite book|url=https://www.ncbi.nlm.nih.gov/books/NBK493148/|title=Nicotine|last1=Sandhu|first1=Amritpal|last2=Saadabadi|first2=Abdolreza|chapter=Nicotine Replacement Therapy |date=2019-10-10|publisher=StatPearls Publishing|language=en|pmid=29630200}} Some of the medications are:{{Cite journal|last=Flowers|first=Lee|date=2016-06-01|title=Nicotine Replacement Therapy|journal=American Journal of Psychiatry Residents' Journal|volume=11|issue=6|pages=4–7|doi=10.1176/appi.ajp-rj.2016.110602|doi-access=free}}
- Antipsychotic medications
- Heart-related medications
- Caffeine
Contraindications and precautions
Nicotine replacement therapy cannot be used in those with any type of nicotine sensitivity.{{Cite web|url=https://medlineplus.gov/druginfo/meds/a606019.html|title=Nicotine Lozenges: MedlinePlus Drug Information|website=medlineplus.gov|language=en|access-date=2019-11-06}} Nicotine lozenge should not be used in those with soy allergies.
Pregnant women or women who are breast feeding should speak with their health care providers and get their approval before using nicotine lozenges.
Nicotine lozenge should be used in caution in those with the following:
- Diabetes
- Heart disease
- Asthma
- Stomach ulcers
- A recent heart attack
- High blood pressure
- A history of irregular heartbeat
- Mouth problems
- Been prescribed another medication to help quit smoking
Symptoms of overdose
Storage and disposal
It is recommended that nicotine lozenges be kept in the original container, at room temperature and away from excessive heat or moisture. The container should be stored in a secure location away from children or pets.
Unused lozenges should be taken to a medication take-back program or otherwise disposed of in accordance with applicable laws.
See also
References
{{Reflist}}
External links
- [http://www.cancer.gov/dictionary?CdrID=441271 Nicotine lozenge] entry in the public domain NCI Dictionary of Cancer Terms
{{NCI-cancer-dict}}