Nidogen-2
{{Short description|Protein-coding gene in the species Homo sapiens}}
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Nidogen-2, also known as osteonidogen, is a basal lamina protein of the nidogen family. It was the second nidogen to be described after nidogen-1 (entactin). Both play key roles during late embryonic development.{{cite journal | vauthors = Miosge N, Holzhausen S, Zelent C, Sprysch P, Herken R | title = Nidogen-1 and nidogen-2 are found in basement membranes during human embryonic development | journal = The Histochemical Journal | volume = 33 | issue = 9–10 | pages = 523–30 | year = 2002 | pmid = 12005023 | doi = 10.1023/A:1014995523521 | s2cid = 818451 }} In humans it is encoded by the NID2 gene.{{cite journal | vauthors = Kohfeldt E, Sasaki T, Göhring W, Timpl R | title = Nidogen-2: a new basement membrane protein with diverse binding properties | journal = Journal of Molecular Biology | volume = 282 | issue = 1 | pages = 99–109 | date = Sep 1998 | pmid = 9733643 | doi = 10.1006/jmbi.1998.2004 }}{{cite web | title = Entrez Gene: NID2 nidogen 2 (osteonidogen)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22795}}
References
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Further reading
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- {{cite journal | vauthors = Ulazzi L, Sabbioni S, Miotto E, Veronese A, Angusti A, Gafà R, Manfredini S, Farinati F, Sasaki T, Lanza G, Negrini M | title = Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer | journal = Molecular Cancer | volume = 6 | issue = 1 | pages = 17 | year = 2007 | pmid = 17328794 | pmc = 1831485 | doi = 10.1186/1476-4598-6-17 | doi-access = free }}
- {{cite journal | vauthors = Nischt R, Schmidt C, Mirancea N, Baranowsky A, Mokkapati S, Smyth N, Woenne EC, Stark HJ, Boukamp P, Breitkreutz D | title = Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture | journal = The Journal of Investigative Dermatology | volume = 127 | issue = 3 | pages = 545–54 | date = Mar 2007 | pmid = 17008882 | doi = 10.1038/sj.jid.5700562 | doi-access = free }}
- {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}
- {{cite journal | vauthors = Miosge N, Sasaki T, Timpl R | title = Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice | journal = Matrix Biology | volume = 21 | issue = 7 | pages = 611–21 | date = Nov 2002 | pmid = 12475645 | doi = 10.1016/S0945-053X(02)00070-7 }}
- {{cite journal | vauthors = Tu H, Sasaki T, Snellman A, Göhring W, Pirilä P, Timpl R, Pihlajaniemi T | title = The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin | journal = The Journal of Biological Chemistry | volume = 277 | issue = 25 | pages = 23092–9 | date = Jun 2002 | pmid = 11956183 | doi = 10.1074/jbc.M107583200 | doi-access = free }}
- {{cite journal | vauthors = Sasaki T, Göhring W, Mann K, Brakebusch C, Yamada Y, Fässler R, Timpl R | title = Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins | journal = Journal of Molecular Biology | volume = 314 | issue = 4 | pages = 751–63 | date = Dec 2001 | pmid = 11733994 | doi = 10.1006/jmbi.2001.5176 }}
- {{cite journal | vauthors = Sasaki T, Göhring W, Miosge N, Abrams WR, Rosenbloom J, Timpl R | title = Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins | journal = FEBS Letters | volume = 460 | issue = 2 | pages = 280–4 | date = Oct 1999 | pmid = 10544250 | doi = 10.1016/S0014-5793(99)01362-9 | s2cid = 25139630 | doi-access = }}
- {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = Sep 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 | doi-access = free }}
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