Niludipine

{{chembox

| verifiedrevid = 392775255

| ImageFile=File:Niludipine.svg

| ImageSize=250px

| PIN = Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

| OtherNames = 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid bis(2-propoxyethyl) ester

|Section1={{Chembox Identifiers

| CASNo=22609-73-0

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 9844OS3B0J

| PubChem= 89767

| SMILES=CCCOCCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOCCC)C)C

| EINECS = 245-120-6

| ChemSpiderID = 81025

| InChI = 1/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3

| InChIKey = VZWXXKDFACOXNT-UHFFFAOYAS

| StdInChI = 1S/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3

| StdInChIKey = VZWXXKDFACOXNT-UHFFFAOYSA-N

| RTECS =

| MeSHName = C019497

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|Section2={{Chembox Properties

| C=25 | H=34 | N=2 | O=8

| Appearance=

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|Section3={{Chembox Hazards

| MainHazards=

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Niludipine is a calcium channel blocker of the dihydropyridine class. It is a vasodilator that acts upon the coronary arteries of the heart-lung. It was found to produce a calcium antagonistic effect on the smooth muscle of hearts of canines and guinea pigs inhibiting myocardial oxidative metabolism.{{cite journal |last1=Hashimoto |first1=K |title=Effects of niludipine on the Cardiovascular system with a note on its Calcium-Antagonistic effects. |journal=Arzneimittel-Forschung |volume=29 |issue=9 |pages=1368–73 | pmid = 583243|year=1979 }}

References