Nottingham Prognostic Index

The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer.{{Cite journal|last1=Griffiths|first1=K.|last2=Nicholson|first2=R. I.|last3=Campbell|first3=F. C.|last4=P. J. Doyle|last5=Johnson|first5=J.|last6=Elston|first6=C. W.|last7=Blamey|first7=R. W.|last8=Haybittle|first8=J. L.|year=1982|title=A prognostic index in primary breast cancer|journal=British Journal of Cancer|language=en|volume=45|issue=3|pages=361–366|doi=10.1038/bjc.1982.62|issn=1532-1827|pmid=7073932|pmc=2010939}}{{Cite journal|last1=Haybittle|first1=J. L.|last2=Blamey|first2=R. W.|last3=Hinton|first3=C. P.|last4=I. O. Ellis|last5=Elston|first5=C. W.|last6=Williams|first6=M. R.|last7=Dowle|first7=C.|last8=Todd|first8=J. H.|year=1987|title=Confirmation of a prognostic index in primary breast cancer|journal=British Journal of Cancer|language=en|volume=56|issue=4|pages=489–492|doi=10.1038/bjc.1987.230|pmid=3689666|issn=1532-1827|pmc=2001834}} Its value is calculated using three pathological criteria: the size of the tumour; the number of involved lymph nodes; and the grade of the tumour. It is calculated to select patients for adjuvant treatment.