Nova Scotia Route 221

{{short description|Highway in Nova Scotia, Canada}}

{{Infobox road

|province=NS

|type=Route

|route=221

|alternate_name=

|maint=Nova Scotia Department of Transportation and Infrastructure Renewal

|length_km=63

|length_round=1

|length_ref= Atlantic Canada Back Road Atlas {{ISBN|978-1-55368-618-7}} Pages 65-66, 78

|established=

|direction_a=West

|direction_b=East

|terminus_a={{jct|state=NS|Route|362}} in Spa Springs

|terminus_b=Medford Road in Kingsport

|counties=Annapolis / Kings

|previous_type=Route

|previous_route=219

|next_type=Route

|next_route=223

}}

Image:NSRoute221 3.png]]

Route 221 is a collector road in the Canadian province of Nova Scotia.

It is located in Kings County and Annapolis County in the Annapolis Valley and connects Kingsport to Spa Springs.

Valley residents informally refer to Route 221 as the "Back Road", since it runs parallel to Trunk 1, but instead of running through the centre of the valley, it runs close to the less-populated southern base of the North Mountain.